Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

3,097 questions · 3,266 findings · 631 reviews

No studies found 430 · 13.2%GRADE not reported 193 · 5.9%Very low 995 · 30.5%Low 904 · 27.7%Moderate 591 · 18.1%High 153 · 4.7%

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Lymphoma/PTLD · primary immunosuppression in kidney transplant recipients

Low showed no clear difference in lymphoma/PTLD compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (moderate certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Acne/rash · primary immunosuppression in kidney transplant recipients

Low showed no clear difference in acne/rash compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (low certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Hypercholesterolaemia · primary immunosuppression in kidney transplant recipients

Low probably leads to lower hypercholesterolaemia compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (moderate certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Anaemia · primary immunosuppression in kidney transplant recipients

Low may leads to lower anaemia compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (low certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Thrombocytopenia · primary immunosuppression in kidney transplant recipients

Low may leads to lower thrombocytopenia compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (low certainty).

1 finding from 1 review

Combined spinal‐epidural vs high‐dose spinal

Number of women requiring a repeat regional block or a general anaesthetic as a result of failure to establish adequate initial blockade · women undergoing caesarean section

Combined spinal‐epidural showed no clear difference in number of women requiring a repeat regional block or a general… compared with high‐dose spinal (low certainty).

1 finding from 1 review

Combined spinal‐epidural vs high‐dose spinal

Number of women requiring supplemental intra‐operative analgesia at any time after CSE or spinal anaesthetic insertion · women undergoing caesarean section

It is very uncertain whether combined spinal‐epidural changes number of women requiring supplemental intra‐operative analgesia at… compared with high‐dose spinal (very low certainty).

1 finding from 1 review

Combined spinal‐epidural vs high‐dose spinal

Number of women requiring intra‐operative conversion to general anaesthesia · women undergoing caesarean section

It is very uncertain whether combined spinal‐epidural changes number of women requiring intra‐operative conversion to general… compared with high‐dose spinal (very low certainty).

1 finding from 1 review

Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (> 140 mM)

Intradialytic hypotension · chronic HD

Low dialysate [Na+] (< 138 mM) probably leads to higher intradialytic hypotension compared with neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (>… (moderate certainty).

1 finding from 1 review