Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,661 questions · 2,751 findings · 453 reviews

No studies found 593 · 21.6%GRADE not reported 277 · 10.1%Very low 538 · 19.6%Low 712 · 25.9%Moderate 516 · 18.8%High 115 · 4.2%

Tibolone vs combined HT

Breast cancer; women without previous breast cancer (all doses) · postmenopausal women with or without vasomotor symptoms

It is very uncertain whether tibolone changes breast cancer; women without previous breast cancer (all doses) compared with combined HT (very low certainty).

1 finding from 1 review

Tibolone vs placebo

Breast cancer; women without previous breast cancer (all doses) · postmenopausal women with or without vasomotor symptoms

It is very uncertain whether tibolone changes breast cancer; women without previous breast cancer (all doses) compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Behavioural outcome: immunisation rate ATCS Plus, IVR, unidirectional versus no calls, letters, usual care at median · participants at risk of under‐immunisation (children, adolescents and adults)

The intervention probably leads to higher behavioural outcome: immunisation rate ATCS Plus, IVR,… (moderate certainty).

1 finding from 1 review