Low dialysate [Na+] (< 138 mM) vs high dialysate [Na+] (> 140 mM)
Postdialysis MAP · chronic HD
1 finding from 1 review
- no estimate extracted2 studies · 38 participantsLow
Findings
What do systematic reviews say?
3,006 questions · 3,171 findings · 607 reviews · Headline outcomes only
No studies found 411 · 13%GRADE not reported 153 · 4.8%Very low 968 · 30.5%Low 897 · 28.3%Moderate 589 · 18.6%High 153 · 4.8%
Low dialysate [Na+] (< 138 mM) vs high dialysate [Na+] (> 140 mM)
Antihypertensive medication · chronic HD
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (> 140 mM)
Intradialytic hypotension · chronic HD
Low dialysate [Na+] (< 138 mM) probably leads to higher intradialytic hypotension compared with neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (>… (moderate certainty).
1 finding from 1 review
- RR 1.52 [1.14, 2.02]7 studies · 12570 participantsModerate
Low dialysate [Na+] (< 138 mM) vs high dialysate [Na+] (> 140 mM)
Predialysis serum [Na+] · chronic HD
1 finding from 1 review
- no estimate extracted4 studies · 89 participantsModerate
Low dialysate [Na+] (< 138 mM) vs high dialysate [Na+] (> 140 mM)
Intradialytic cramps · chronic HD
Low dialysate [Na+] (< 138 mM) may leads to higher intradialytic cramps compared with high dialysate [Na+] (> 140 mM) (low certainty).
1 finding from 1 review
- RR 1.94 [1.54, 2.44]2 studies · 486 participantsLow
Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (> 140 mM)
Predialysis MAP · chronic HD
1 finding from 1 review
- no estimate extracted4 studies · 156 participantsModerate
Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (> 140 mM)
Postdialysis MAP · chronic HD
1 finding from 1 review
- no estimate extracted4 studies · 150 participantsModerate
Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (> 140 mM)
Antihypertensive medication · chronic HD
1 finding from 1 review
- no estimate extracted2 studies · 103 participantsLow
Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (> 140 mM)
Predialysis serum [Na+] · chronic HD
1 finding from 1 review
- no estimate extracted7 studies · 258 participantsModerate
Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (> 140 mM)
Intradialytic cramps · chronic HD
Low dialysate [Na+] (< 138 mM) probably leads to higher intradialytic cramps compared with neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (>… (moderate certainty).
1 finding from 1 review
- RR 1.77 [1.15, 2.73]6 studies · 12186 participantsModerate
Intervention not reported
Typical antipsychotic vs placebo · critically ill adults with confirmed or at high risk of delirium
1 finding from 1 review
- Pharmacological interventions for the treatment of delirium in critically ill adults 2019 · Cochrane Headline outcomes onlyno estimate extracted4 studies · 608 participantsHigh
Intervention not reported
Typical antipsychotics vs placebo · critically ill adult with confirmed or at high risk of delirium
1 finding from 1 review
- Pharmacological interventions for the treatment of delirium in critically ill adults 2019 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 515 participantsModerate
Intervention not reported
Atypical antipsychotics vs placebo · critically ill adult with confirmed or at high risk of delirium
1 finding from 1 review
- Pharmacological interventions for the treatment of delirium in critically ill adults 2019 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 476 participantsModerate
Intervention not reported
Statin (HMG‐CoA)vs placebo · critically ill adult with confirmed or at high risk of delirium
1 finding from 1 review
- Pharmacological interventions for the treatment of delirium in critically ill adults 2019 · Cochrane Headline outcomes onlyno estimate extracted1 study · 272 participantsModerate
Intervention not reported
Alpha2 agonist vs placebo · critically ill adult with confirmed or at high risk of delirium
1 finding from 1 review
- Pharmacological interventions for the treatment of delirium in critically ill adults 2019 · Cochrane Headline outcomes onlyno estimate extracted1 study · 71 participantsModerate
Intervention not reported
Opioid vs placebo · critically ill adult with confirmed or at high risk of delirium
1 finding from 1 review
- Pharmacological interventions for the treatment of delirium in critically ill adults 2019 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsVery low
Intervention not reported
Typical antipsychotic vs placebo · critically ill adult with confirmed or at high risk of delirium
1 finding from 1 review
- Pharmacological interventions for the treatment of delirium in critically ill adults 2019 · Cochrane Headline outcomes onlyno estimate extracted4 studies · 618 participantsModerate
Intervention not reported
Atypical antipsychotic vs placebo · critically ill adult with confirmed or at high risk of delirium
1 finding from 1 review
- Pharmacological interventions for the treatment of delirium in critically ill adults 2019 · Cochrane Headline outcomes onlyno estimate extracted4 studies · 577 participantsHigh
Intervention not reported
Statin (HMG‐CoA) vs placebo · critically ill adult with confirmed or at high risk of delirium
1 finding from 1 review
- Pharmacological interventions for the treatment of delirium in critically ill adults 2019 · Cochrane Headline outcomes onlyno estimate extracted1 study · 272 participantsLow
Intervention not reported
Alpha2 agonist vs placebo · critically ill adult with confirmed or at high risk of delirium
1 finding from 1 review
- Pharmacological interventions for the treatment of delirium in critically ill adults 2019 · Cochrane Headline outcomes onlyno estimate extracted1 study · 71 participantsLow