Graft loss including death · primary immunosuppression in kidney transplant recipients
Low showed no clear difference in total graft loss (with death) compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (moderate certainty).
1 finding from 1 review
Biopsy‐proven acute rejection · primary immunosuppression in kidney transplant recipients
Low probably leads to higher biopsy‐proven acute rejection compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (moderate certainty).
1 finding from 1 review
CMV infection · primary immunosuppression in kidney transplant recipients
Low showed no clear difference in CMV infection compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (moderate certainty).
1 finding from 1 review
Malignancy · primary immunosuppression in kidney transplant recipients
Low showed no clear difference in all malignancy compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (moderate certainty).
1 finding from 1 review
Number needing to change treatment · primary immunosuppression in kidney transplant recipients
Low showed no clear difference in number needing to change treatment compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (low certainty).
1 finding from 1 review
Diabetes · primary immunosuppression in kidney transplant recipients
Low probably leads to lower diabetes compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (moderate certainty).
1 finding from 1 review
Lymphoma/PTLD · primary immunosuppression in kidney transplant recipients
Low showed no clear difference in lymphoma/PTLD compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (moderate certainty).
1 finding from 1 review
Acne/rash · primary immunosuppression in kidney transplant recipients
Low showed no clear difference in acne/rash compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (low certainty).
1 finding from 1 review
GRF (mL/min) · primary immunosuppression in kidney transplant recipients
1 finding from 1 review
Hypercholesterolaemia · primary immunosuppression in kidney transplant recipients
Low probably leads to lower hypercholesterolaemia compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (moderate certainty).
1 finding from 1 review
Anaemia · primary immunosuppression in kidney transplant recipients
Low may leads to lower anaemia compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (low certainty).
1 finding from 1 review
Thrombocytopenia · primary immunosuppression in kidney transplant recipients
Low may leads to lower thrombocytopenia compared with higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes (low certainty).
1 finding from 1 review
Number of women requiring a repeat regional block or a general anaesthetic as a result of failure to establish adequate initial blockade · women undergoing caesarean section
Combined spinal‐epidural showed no clear difference in number of women requiring a repeat regional block or a general… compared with high‐dose spinal (low certainty).
1 finding from 1 review
Number of women requiring supplemental intra‐operative analgesia at any time after CSE or spinal anaesthetic insertion · women undergoing caesarean section
It is very uncertain whether combined spinal‐epidural changes number of women requiring supplemental intra‐operative analgesia at… compared with high‐dose spinal (very low certainty).
1 finding from 1 review
Number of women requiring intra‐operative conversion to general anaesthesia · women undergoing caesarean section
It is very uncertain whether combined spinal‐epidural changes number of women requiring intra‐operative conversion to general… compared with high‐dose spinal (very low certainty).
1 finding from 1 review
Number of women satisfied with anaesthesia · women undergoing caesarean section
It is very uncertain whether combined spinal‐epidural changes number of women satisfied with anaesthesia compared with high‐dose spinal (very low certainty).
1 finding from 1 review
IDWG · chronic HD
1 finding from 1 review
IDWG · chronic HD
1 finding from 1 review
Intradialytic hypotension · chronic HD
Low dialysate [Na+] (< 138 mM) showed no clear difference in intradialytic hypotension compared with high dialysate [Na+] (> 140 mM) (low certainty).
1 finding from 1 review
Predialysis MAP · chronic HD
1 finding from 1 review