Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,752 questions · 6,648 findings · 688 reviews

No studies found 1,125 · 16.9%GRADE not reported 670 · 10.1%Very low 1,796 · 27%Low 1,685 · 25.3%Moderate 1,075 · 16.2%High 297 · 4.5%

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Full opioid agonists vs different full opioid agonists or partial opioid agonists (methadone versus buprenorphine)

Adverse effects · pharmaceutical opioid dependent people

Full opioid agonists showed no clear difference in adverse effects compared with different full opioid agonists or partial opioid agonists (methadone… (low certainty).

1 finding from 1 review

Antihistamines vs antiemetics

Proportion of susceptible participants who did not experience any motion sickness symptoms under experimental conditions Assessed by: calculated based on head movements tolerated (rotating chair); MSAQ · patients with motion sickness
1 finding from 1 review

Antihistamines vs antiemetics

Proportion of susceptible participants who experienced a reduction or resolution of existing motion sickness symptoms · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs antiemetics

Physiological measures: heart rate and core temperature · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs antiemetics

Adverse effects: impaired cognition and blurred vision · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Utilization—at 6 months postabortion · women who experienced abortions and requested a reversible contraceptive method

Immediate may leads to higher utilization—at 6 months postabortion compared with delayed postabortion insertion of contraceptive implants (low certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Unintended pregnancy · women who experienced abortions and requested a reversible contraceptive method

Immediate probably leads to lower unintended pregnancy—at 6 months postabortion compared with delayed postabortion insertion of contraceptive implants (moderate certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Rate of initiation of contraceptive implants—following medical abortion at · women who experienced abortions and requested a reversible contraceptive method

Immediate probably leads to higher rate of initiation of contraceptive implants—following medical… compared with delayed postabortion insertion of contraceptive implants (moderate certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Rate of initiation of contraceptive implants—following surgical abortion at · women who experienced abortions and requested a reversible contraceptive method

Immediate may leads to higher rate of initiation of contraceptive implants—following surgical… compared with delayed postabortion insertion of contraceptive implants (low certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Failure rate of medical abortion—overall failure rate at · women who experienced abortions and requested a reversible contraceptive method

Immediate showed no clear difference in failure rate of medical abortion—overall failure rate at compared with delayed postabortion insertion of contraceptive implants (moderate certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Failure rate of medical abortion—require extra medication for complete abortion at · women who experienced abortions and requested a reversible contraceptive method

Immediate showed no clear difference in failure rate of medical abortion—require extra medication for… compared with delayed postabortion insertion of contraceptive implants (low certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Failure rate of medical abortion—require surgery for complete abortion at · women who experienced abortions and requested a reversible contraceptive method

Immediate showed no clear difference in failure rate of medical abortion—require surgery for complete… compared with delayed postabortion insertion of contraceptive implants (moderate certainty).

1 finding from 1 review

Immediate vs delayed postabortion insertion of contraceptive implants

Bleeding side effects—at 1 month postabortion · women who experienced abortions and requested a reversible contraceptive method

Immediate showed no clear difference in bleeding side effects—at 1 month postabortion compared with delayed postabortion insertion of contraceptive implants (low certainty).

1 finding from 1 review

Dental examinations at three-month intervals and preventive treatments vs usual care

MRONJ (incidence rate: cases per patient-year) · Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ)

It is very uncertain whether dental examinations at three-month intervals and preventive treatments changes MRONJ (incidence rate: cases per patient-year) compared with standard care (very low certainty).

1 finding from 1 review

Selective carious tissue removal (selective excavation, SE) vs Hall Technique (sealing with a preformed metal crown)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

It is very uncertain whether selective carious tissue removal (selective excavation, SE) changes failure of therapy compared with hall Technique (sealing with a preformed metal crown) (very low certainty).

2 findings from 1 review

Non-selective carious tissue removal and conventional restoration (CR) vs Hall Technique (sealing with a preformed metal crown)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

Non-selective carious tissue removal and conventional restoration (CR) may leads to higher failure of therapy compared with hall Technique (sealing with a preformed metal crown) (low certainty).

1 finding from 1 review

Non-selective carious tissue removal and conventional restoration (CR) vs Hall Technique (sealing with a preformed metal crown)

Efficiency, costs or cost-effectiveness · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
1 finding from 1 review