Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,543 questions · 2,589 findings · 168 reviews · Schizophrenia

No studies found 601 · 23.2%GRADE not reported 446 · 17.2%Very low 721 · 27.8%Low 505 · 19.5%Moderate 274 · 10.6%High 42 · 1.6%

Day hospitals vs Inpatient

Extent of hospital care: 5. readmitted to in/day patient care after discharge · patients with acute psychiatric disorders

It is very uncertain whether day hospital changes extent of hospital care: 5. readmitted to in/day patient care after… compared with inpatient (very low certainty).

1 finding from 1 review

PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM vs SPECIALISED TEAM

Progression to psychosis ‐ by 12 months · people with psychosis

PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM probably leads to lower progression to psychosis ‐ by 6 months compared with SPECIALISED TEAM (moderate certainty).

2 findings from 1 review

SPECIALISED TEAM vs usual care

Compliance with treatment ‐ treatment stopped in spite of need ‐ by one year · people with psychosis

SPECIALISED TEAM probably leads to lower compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Compliance with treatment ‐ treatment stopped in spite of need ‐ by two years · people with psychosis

SPECIALISED TEAM showed no clear difference in compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Service use: 2. Not hospitalised ‐ by five years · people with psychosis

SPECIALISED TEAM showed no clear difference in service use: 2. Not hospitalised ‐ by five years compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Social outcomes: 1. Not living independently ‐ by 5 years · people with psychosis

SPECIALISED TEAM probably leads to lower social outcomes: 1. Not living independently ‐ by 5 years compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Social outcomes: 2. Not working or in education ‐ by 5 years · people with psychosis

SPECIALISED TEAM showed no clear difference in social outcomes: 2. Not working or in education ‐ by 5 years compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

Intervention not reported

Poor compliance with study protocol · people with schizophrenia or like psychosis

The intervention may leads to lower poor compliance with study protocol (low certainty).

1 finding from 1 review

Intervention not reported

Relapse · people with schizophrenia or like psychosis

The intervention may leads to lower relapse (low certainty).

1 finding from 1 review

Intervention not reported

Weight gain (equal or greater then 7% of baseline) · people with schizophrenia or like psychosis

The intervention may leads to higher weight gain (equal or greater then 7% of baseline) (low certainty).

1 finding from 1 review

Intervention not reported

Concomitant medication (Anxiolytic ‐ Lorazepam) · people with schizophrenia or like psychosis

The intervention may leads to lower concomitant medication (Anxiolytic ‐ Lorazepam) (low certainty).

1 finding from 1 review