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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Single-stage alginate impression (simplified method) vs Two stage-two step elastomer (silicone, polysulfide, or polyether) conventional method

Mandibular denture satisfaction · Completely edentulous people

It is very uncertain whether single-stage alginate impression (simplified method) changes mandibular denture satisfaction compared with two stage-two step elastomer (silicone, polysulfide, or polyether)… (very low certainty).

1 finding from 1 review

4% prilocaine plain vs 2% lidocaine, 1:100,000 epinephrine

Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review
  • SoF: See comment; 0 participants (0 studies); 1 case of prolonged anaesthesia recorded; no clinical studies met the outcome definition (unable to confirm whether prolonged anaesthesia = paraesthesia).
    0 studies
    No studies found

Ferric sulphate (FS)/zinc oxide and eugenol (ZOE) pulpotomy vs Sedanol (ZOE) pulpectomy

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Ferric sulphate (FS)/zinc oxide and eugenol (ZOE) pulpotomy showed no clear difference in radiological failure compared with sedanol (ZOE) pulpectomy; GRADE not reported.

1 finding from 1 review

Chemical cured composite vs Light-cured compomer (polyacid-modified composite resin)

Decalcification · Patients with fixed orthodontic appliances attached to their teeth
1 finding from 1 review
  • Adhesives for fixed orthodontic brackets 2018 · Cochrane All outcomes
    To end of appliance treatment
    However the paper reported that the compomer offered better protection against decalcification when compared by a sign test (P = 0.0075) (Millett 2000). No effect estimate or confidence interval was reported.
    1 study · 45 participants
    GRADE not reported

5.3% HP strip vs 5% HP gel in tray

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 5.3% HP strip changes tooth whitening - assessed by the dentist compared with 5% HP gel in tray (very low certainty).

1 finding from 1 review

6% HP strip vs 19% SPC paint-on film

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

6% HP strip led to higher tooth whitening - assessed by the dentist compared with 19% SPC paint-on film; GRADE not reported.

1 finding from 1 review

Electrofulguration + calcium hydroxide (CH) vs Electrofulguration + zinc oxide and eugenol (ZOE)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Electrofulguration + calcium hydroxide (CH) showed no clear difference in clinical failure compared with electrofulguration + zinc oxide and eugenol (ZOE); GRADE not reported.

1 finding from 1 review

Enhanced one-to-one OHA vs Routine one-to-one OHA

Gingivitis · Children or adults (fit and healthy, or with a well-defined medical condition)

It is very uncertain whether enhanced one-to-one OHA changes periodontal health: gingivitis compared with one-to-one OHA (standard) (very low certainty).

1 finding from 1 review

5% CP gel in tray (with STPP) vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 5% CP gel in tray (with STPP) changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).

1 finding from 1 review

4% articaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Success of local anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% articaine, 1:200,000 epinephrine changes success of local anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

2% lidocaine, 1:50,000 epinephrine vs 2% lidocaine, 1:80,000 epinephrine

Success of local anaesthesia (pulpal, electric pulp tester; healthy pulps) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 2% lidocaine, 1:50,000 epinephrine changes success of local anaesthesia (pulpal, electric pulp tester; healthy… compared with 2% lidocaine, 1:80,000 epinephrine (very low certainty).

1 finding from 1 review

10% CP gel in tray vs 10% CP gel in tray

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 10% CP gel in tray (Opalescence) changes tooth whitening - assessed by the dentist compared with 10% CP gel in tray (NiteWhite Excel) (very low certainty).

1 finding from 1 review

Sedation

Outcome not reported · Medically compromised children (ASA III+) or children with learning/behavioural difficulties needing dental treatment

The review found no eligible studies for this question.

1 finding from 1 review
  • 'Some of the techniques described may be useful in the management of medically compromised patients, but at present there are no studies carried out in these groups.' (Discussion) Explicit evidence gap.
    0 studies
    No studies found

Ball (stud) attachment system vs Telescopic attachment system

Patient satisfaction / quality of life (validated measure) · Edentulous adults receiving mandibular implant overdentures (opposing conventional complete maxillary dentures)
1 finding from 1 review