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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,173 questions in 89 reviews · Neuromuscular

current versions
No studies 302 · 25.7%Ungraded 119 · 10.1%Very low 267 · 22.8%Low 239 · 20.4%Moderate 177 · 15.1%High 69 · 5.9%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Acupuncture plus non‐gastrokinetic agents vs non‐gastrokinetic agents alone
Changes of medication for gastroparesis (either short or long term) ‐ not measured · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus non‐gastrokinetic agents vs non‐gastrokinetic agents alone
Quality of life (either short or long term) ‐ not measured · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus non‐gastrokinetic agents vs non‐gastrokinetic agents alone
Adverse events ‐ not reported · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus routine care/diabetes control vs the same treatment alone (routine care/diabetes control)
Improvement in symptoms of gastroparesis (short term: 4 to 12 weeks) · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus routine care/diabetes control vs the same treatment alone (routine care/diabetes control)
Improvement in symptoms of gastroparesis (long term: more than 12 weeks) ‐ not measured · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus routine care/diabetes control vs the same treatment alone (routine care/diabetes control)
Proportion of people whose symptoms 'improved' (short term: 4 to 12 weeks) · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
RR 1.47 [1.06, 2.04]3 studies · 217 participantsVery low
Acupuncture plus routine care/diabetes control vs the same treatment alone (routine care/diabetes control)
Proportion of people whose symptoms 'improved' (long term: more than 12 weeks) ‐ not measured · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs sham acupuncture
Proportion of people whose symptoms 'improved' (long term: more than 12 weeks) ‐ not measured · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus routine care/diabetes control vs the same treatment alone (routine care/diabetes control)
Changes of medication for gastroparesis (either short or long term) ‐ not measured · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus routine care/diabetes control vs the same treatment alone (routine care/diabetes control)
Quality of life (either short or long term) ‐ not measured · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus routine care/diabetes control vs the same treatment alone (routine care/diabetes control)
Adverse events ‐ not reported · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs sham acupuncture
Changes of medication for gastroparesis (either short or long term) ‐ not measured · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs sham acupuncture
Quality of life (either short or long term) ‐ not measured · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs sham acupuncture
Adverse events · symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extracted1 study · 60 participantsLow
Acupuncture vs gastrokinetic agents
Improvement in symptoms of gastroparesis (short term: 4 to 12 weeks) · people with symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extracted5 studies · 360 participantsVery low
Acupuncture vs gastrokinetic agents
Improvement in symptoms of gastroparesis (long term: more than 12 weeks) ‐ not measured · people with symptomatic gastroparesis
Acupuncture for symptomatic gastroparesis (2018) · Cochrane
no estimate extractedNRNo studies
Modafinil vs placebo
Fatigue · people with ALS/MND
Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease (2018) · Cochrane
no estimate extracted1 study · 32 participantsVery low
Modafinil vs placebo
Adverse events · people with ALS/MND
Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease (2018) · Cochrane
no estimate extracted1 study · 32 participantsVery low
Exercise vs usual care
Fatigue · people with ALS/MND
Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease (2018) · Cochrane
no estimate extracted1 study · 18 participantsVery low
Exercise vs usual care
Adverse events · people with ALS/MND
Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease (2018) · Cochrane
no estimate extracted1 study · 18 participantsVery low
Inspiratory muscle training vs sham intervention
Fatigue · people with ALS/MND
Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease (2018) · Cochrane
no estimate extracted1 study · 24 participantsVery low
Inspiratory muscle training vs sham intervention
Adverse events · people with ALS/MND
Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease (2018) · Cochrane
no estimate extracted1 study · 24 participantsVery low
Repetitive transcranial magnetic stimulation (rTMS) vs sham intervention
Fatigue · people with ALS/MND
Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease (2018) · Cochrane
no estimate extracted1 study · 10 participantsVery low
Repetitive transcranial magnetic stimulation (rTMS) vs sham intervention
Adverse events · people with ALS/MND
Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease (2018) · Cochrane
no estimate extracted1 study · 10 participantsVery low
Acupuncture vs placebo/sham acupuncture
Overall clinical improvement at short‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 111 participantsVery low
Acupuncture vs oral corticosteroid
Overall clinical improvement at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 77 participantsVery low
Acupuncture vs oral corticosteroid
Overall clinical improvement at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
RR 1.34 [1.05, 1.72]1 study · 77 participantsVery low
Acupuncture vs oral corticosteroid
Overall clinical improvement at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
RR 1.73 [1.22, 2.45]1 study · 77 participantsVery low
Acupuncture vs oral corticosteroid
Adverse events · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
RR 0.29 [0.06, 1.32]1 study · 77 participantsVery low
Acupuncture vs vitamin B12
Overall clinical improvement at short‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
RR 1.16 [0.99, 1.36]2 studies · 100 participantsVery low
Acupuncture vs vitamin B12
Overall clinical improvement at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs vitamin B12
Adverse events · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extractedNRLow
Acupuncture vs ibuprofen
Overall clinical improvement at short‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Acupuncture vs ibuprofen
Improvement in functional status at short‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Acupuncture vs ibuprofen
Improvement in pain at short‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Acupuncture vs placebo/sham acupuncture
Overall clinical improvement at short‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 41 participantsLow
Acupuncture vs ibuprofen
Adverse events · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Electroacupuncture vs night splints
Overall clinical improvement at short‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 60 participantsVery low
Electroacupuncture vs night splints
Overall clinical improvement at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extractedNRNo studies
Electroacupuncture vs night splints
Adverse events · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
RR 13 [0.76, 220.96]1 study · 60 participantsVery low
Electroacupuncture plus night splints vs night splints alone
Overall clinical improvement at short‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 181 participantsLow
Electroacupuncture plus night splints vs night splints alone
Overall clinical improvement at short‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 181 participantsLow
Electroacupuncture plus night splints vs night splints alone
Overall clinical improvement at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 181 participantsLow
Electroacupuncture plus night splints vs night splints alone
Overall clinical improvement of functional status at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 181 participantsLow
Electroacupuncture plus night splints vs night splints alone
Adverse events · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 181 participantsLow
Acupuncture plus NSAID plus vitamins vs NSAID plus vitamins
Overall clinical improvement at short‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extracted1 study · 80 participantsVery low
Acupuncture vs placebo/sham acupuncture
Overall clinical improvement (at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus NSAID plus vitamins vs NSAID plus vitamins
Overall clinical improvement at long‐term · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture plus NSAID plus vitamins vs NSAID plus vitamins
Adverse events · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
no estimate extractedNRNo studies
Acupuncture vs placebo/sham acupuncture
Adverse events · carpal tunnel syndrome
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome (2018) · Cochrane
RR 2.86 [0.12, 66.44]1 study · 41 participantsLow