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What do systematic reviews say?

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Evidence found and GRADE certainty

657 questions · 681 findings · 36 reviews · Oral and maxillofacial surgery

No studies found 188 · 27.6%GRADE not reported 373 · 54.8%Very low 81 · 11.9%Low 27 · 4%Moderate 8 · 1.2%High 4 · 0.6%

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Health‐related quality of life · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

The review found no eligible studies for this question.

1 finding from 1 review

Triangular flap vs Envelope flap

Permanent altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal

It is very uncertain whether triangular flap changes permanent altered tongue, chin, or lip sensation compared with envelope flap (very low certainty).

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Intercanine width · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

Surgical removal (extraction) of asymptomatic disease-free impacted… showed no clear difference in intercanine width (dimensional changes in the dental arch) compared with retention (conservative management) of asymptomatic disease-free… (low certainty).

1 finding from 1 review

Lingual nerve retractor (subperiosteal or Free's) vs No retractor

Permanent altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal

It is very uncertain whether lingual nerve retractor (subperiosteal or Free's) changes permanent altered tongue, chin, or lip sensation compared with no retractor (very low certainty).

1 finding from 1 review

Autologous platelet concentrate (PRP/PRF) in socket vs No blood product (conventional)

Presence of dry socket · Adults with mandibular third molars requiring removal

Autologous platelet concentrate (PRP/PRF) in socket may leads to lower alveolar osteitis compared with no blood product (conventional) (low certainty).

1 finding from 1 review

Primary (complete) wound closure vs Secondary (partial) wound closure

Maximal mouth opening (interincisal distance) · Adults with mandibular third molars requiring removal

Primary (complete) wound closure showed no clear difference in maximum mouth opening (mean) compared with secondary (partial) wound closure; GRADE not reported.

1 finding from 1 review

Mechanical (high-volume) irrigation vs Manual (low-volume) irrigation

Presence of dry socket · Adults with mandibular third molars requiring removal

It is very uncertain whether mechanical (high-volume) irrigation changes alveolar osteitis compared with manual (low-volume) irrigation (very low certainty).

1 finding from 1 review

Piezoelectric bone removal vs Conventional rotary handpiece

Trismus / maximum mouth opening (mean) · Adults with mandibular third molars requiring removal

Piezoelectric bone removal led to higher trismus / maximum mouth opening (mean) compared with conventional rotary handpiece; GRADE not reported.

1 finding from 1 review

Autologous platelet concentrate (PRP/PRF) in socket vs No blood product (conventional)

Postoperative pain (mean) · Adults with mandibular third molars requiring removal

Autologous platelet concentrate (PRP/PRF) in socket showed no clear difference in postoperative pain (mean) compared with no blood product (conventional); GRADE not reported.

1 finding from 1 review