Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,434 questions · 2,594 findings · 269 reviews

No studies found 543 · 20.9%GRADE not reported 191 · 7.4%Very low 676 · 26.1%Low 732 · 28.2%Moderate 399 · 15.4%High 53 · 2%

Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo + standard care

Withdrawals due to any reason · systemic lupus erythematosus

It is very uncertain whether summary of findings table ‐ Exercise plus usual pharmacological care changes withdrawals due to any reason compared with placebo plus usual pharmacological care (very low certainty).

1 finding from 1 review

Advance care planning vs usual care

Completion of documentation by medical staff regarding discussions with participants about ACP processes (yes/no) · people with heart failure with or without their surrogate decision‐makers/carers

Advance care planning may leads to higher completion of documentation by medical staff regarding discussions… compared with usual care (low certainty).

1 finding from 1 review

Professional oral care vs Usual oral care

Incidence of NHAP · Residents of nursing homes and other long-term care facilities
1 finding from 1 review
  • Incidence of NHAP, follow-up 8-30 months, 5018 (5 studies), Low. Not pooled (individual and cluster-randomised designs, varying effect measures and follow-up). Component estimates: Bourigault HR 0.65 (0.29 to 1.46;…
    5 studies · 5018 participants
    Low

Professional oral care vs Usual oral care

Mortality (all‐cause) · Residents of nursing homes and other long-term care facilities
1 finding from 1 review
  • All-cause mortality, follow-up 12-30 months, 3764 (3 studies), Very low. Not pooled. Adachi RR 0.80 (0.40 to 1.58; 88); Juthani-Mehta HR 1.16 (0.88 to 1.53; 834); Zimmerman adjusted IRR 0.83 (0.61 to 1.12; 1606).…
    3 studies · 3764 participants
    Very low

Hospital‐based specialist palliative care vs usual care

Achieving patient preferred place of death (measured by number of patients with home death) · adults with advanced illness and their unpaid caregivers/families

Hospital‐based specialist palliative care may leads to higher achieving patient preferred place of death (measured by number of… compared with usual care (low certainty).

1 finding from 1 review