Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

309 questions · 321 findings · 28 reviews · Headline outcomes only

No studies found 45 · 14%GRADE not reported 21 · 6.5%Very low 91 · 28.3%Low 65 · 20.2%Moderate 82 · 25.5%High 17 · 5.3%

COMPARISON 1. ARIPIPRAZOLE vs RISPERIDONE

Global state: No clinically significant response (as defined by the original studies) · patients with schizophrenia

COMPARISON 3. ARIPIPRAZOLE showed no clear difference in global state: No clinically significant response (as defined by the… compared with RISPERIDONE (low certainty).

1 finding from 1 review

COMPARISON 1. ARIPIPRAZOLE vs ZIPRASIDONE

Global state: No clinically significant response (as defined by the original studies) · patients with schizophrenia

It is very uncertain whether COMPARISON 4. ARIPIPRAZOLE changes global state: No clinically significant response (as defined by the… compared with ZIPRASIDONE (very low certainty).

1 finding from 1 review