Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,288 questions · 3,354 findings · 516 reviews · Headline outcomes only

No studies found 720 · 21.5%GRADE not reported 164 · 4.9%Very low 950 · 28.3%Low 932 · 27.8%Moderate 434 · 12.9%High 154 · 4.6%

Pericyazine vs Typical antipsychotics

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

It is very uncertain whether pericyazine changes adverse events ‐ for specific reasons ‐ Extrapyramidal side effect compared with typical antipsychotic (very low certainty).

1 finding from 1 review

Pericyazine vs Typical antipsychotics

Leaving the study early for specific reasons · patients with schizophrenia

It is very uncertain whether pericyazine changes leaving the study early for specific reasons compared with typical antipsychotic (very low certainty).

1 finding from 1 review

Pericyazine vs atypical antipsychotics

Global state: no improvement ‐ medium termAs defined in each study · patients with schizophrenia

It is very uncertain whether pericyazine changes global state ‐ not improved compared with atypical antipsychotic (very low certainty).

1 finding from 1 review

Pericyazine vs atypical antipsychotics

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

It is very uncertain whether pericyazine changes adverse Effects ‐ Extrapyramidal symptoms compared with atypical antipsychotic (very low certainty).

1 finding from 1 review

Induction: liposomal amphotericin vs Amphotericin B

Clinical success (absence of periapical pathology, tenderness to pressure and fistula formation) at 24 months · adults with HIV and progressive disseminated histoplasmosis

Induction: liposomal amphotericin may leads to higher clinical success compared with amphotericin deoxycholate (low certainty).

1 finding from 1 review

Induction: liposomal amphotericin vs Amphotericin B

Safety outcomes: drug discontinuation · adults with HIV and progressive disseminated histoplasmosis

It is very uncertain whether induction: liposomal amphotericin changes safety outcomes: drug discontinuation compared with amphotericin deoxycholate (very low certainty).

1 finding from 1 review

PFMT added to electrical stimulation vs electrical stimulation alone (excluding implanted electrodes)

Number of women cured · women with urinary incontinence

It is very uncertain whether PFMT added to electrical stimulation changes number of women cured compared with electrical stimulation alone (excluding implanted electrodes) (very low certainty).

1 finding from 1 review

PFMT added to electrical stimulation vs electrical stimulation alone (excluding implanted electrodes)

Number of women reporting incontinence at 1 year or more after treatment (subjective) ‐ not reported · women with urinary incontinence

The review found no eligible studies for this question.

1 finding from 1 review