Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

461 questions · 472 findings · 42 reviews · Neuromuscular

No studies found 93 · 19.7%GRADE not reported 81 · 17.2%Very low 99 · 21%Low 103 · 21.8%Moderate 75 · 15.9%High 21 · 4.4%

Oxcarbazepine vs placebo

At least 50% reduction in pain · painful diabetic neuropathy

It is very uncertain whether oxcarbazepine changes reduction in participant‐reported pain scores by at least 50% from… compared with placebo (very low certainty).

1 finding from 1 review

Oxcarbazepine vs placebo

At least 30% reduction in pain · painful diabetic neuropathy

It is very uncertain whether oxcarbazepine changes reduction in participant‐reported pain scores by at least 30% from… compared with placebo (very low certainty).

1 finding from 1 review

Oxcarbazepine vs placebo

Participants' global impression of their change in pain Participant's global assessment of therapeutic effect, 'much' or 'very much' · painful diabetic neuropathy

It is very uncertain whether oxcarbazepine changes participants' global impression of their change in pain… compared with placebo (very low certainty).

1 finding from 1 review

Oxcarbazepine vs placebo

Serious adverse effects · painful diabetic neuropathy

Oxcarbazepine probably leads to higher serious adverse effects compared with placebo (moderate certainty).

1 finding from 1 review