Remission with topiramate. Number of participants presenting with a rating scale score within the normal range at the endpoint in depressive episodes (8 weeks) · adults with acute affective episodes in bipolar disorder
It is very uncertain whether topiramate as add‐on therapy changes remission with topiramate. Number of participants presenting with a… compared with alternative drug (very low certainty).
1 finding from 1 review
Efficacy: change in scores from baseline to endpoint (12 weeks) on symptom rating scales in the treatment of manic and mixed episodes Lower scores indicate improvement · adults with acute affective episodes in bipolar disorder
1 finding from 1 review
Reduction in physical signs (number of patients without any conversive attacks in last 2 weeks) End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria
It is very uncertain whether paradoxical intention therapy changes reduction in physical signs (number of patients without any… compared with diazepam (very low certainty).
1 finding from 1 review
Level of functioning · people with conversion disorder according to DSM‐IV or ICD‐10 criteria
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · people with conversion disorder according to DSM‐IV or ICD‐10 criteria
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · people with conversion disorder according to DSM‐IV or ICD‐10 criteria
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Reduction in physical signs Decrease in seizure frequency End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria
It is very uncertain whether cognitive behavioural therapy as changes reduction in physical signs Reduction in monthly seizure frequency… compared with standard medical care (very low certainty).
2 findings from 1 review
Reduction in physical sign Seizure freedom as assessed by a daily self‐reported seizure diary End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria
It is very uncertain whether cognitive behavioural therapy as changes reduction in physical sign Seizure freedom as assessed by a daily… compared with standard medical care (very low certainty).
1 finding from 1 review
Level of functioning · people with conversion disorder according to DSM‐IV or ICD‐10 criteria
1 finding from 1 review
Quality of life As assessed by QOLIE31 (higher is better) · people with conversion disorder according to DSM‐IV or ICD‐10 criteria
1 finding from 1 review
Adverse events · people with conversion disorder according to DSM‐IV or ICD‐10 criteria
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Repetition of SH at post‐intervention · self‐harm in adults
Comparison 12.8: Long‐term therapy showed no clear difference in repetition of SH at post‐intervention compared with TAU or another comparator (low certainty).
1 finding from 1 review
Severity of PTSD symptoms ‐ Clinician‐rated · Adults with PTSD for at least 3 months
1 finding from 1 review
Leaving the study early · Adults with PTSD for at least 3 months
It is very uncertain whether trauma‐focused CBT/Exposure therapy changes leaving the study early for any reason compared with waitlist/Usual Care (very low certainty).
1 finding from 1 review
Severity of PTSD symptoms ‐ Clinician‐rated · Adults with PTSD for at least 3 months
1 finding from 1 review
Leaving the study early · Adults with PTSD for at least 3 months
It is very uncertain whether trauma‐focused CBT/Exposure therapy changes leaving the study early for any reason compared with non‐TFCBT (very low certainty).
1 finding from 1 review
Severity of PTSD symptoms ‐ Clinician‐rated · Adults with PTSD for at least 3 months
1 finding from 1 review
Leaving the study early · Adults with PTSD for at least 3 months
It is very uncertain whether trauma‐focused CBT/Exposure therapy changes leaving the study early for any reason compared with other therapies (very low certainty).
1 finding from 1 review
Severity of PTSD symptoms · post‐traumatic stress disorder (PTSD)
1 finding from 1 review
Severity of PTSD symptoms · post‐traumatic stress disorder (PTSD)
1 finding from 1 review