Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

231 questions · 231 findings · 28 reviews · Anaesthesia

No studies found 41 · 17.7%GRADE not reported 10 · 4.3%Very low 35 · 15.2%Low 94 · 40.7%Moderate 35 · 15.2%High 16 · 6.9%

Multiple vs single‐injection technique

Secondary analgesia failure: Intraoperative sedation required · Adult patients undergoing hand, wrist or forearm surgery

Multiple showed no clear difference in secondary analgesia failure ‐ intraoperative sedation required compared with single‐injection technique (high certainty).

1 finding from 1 review

NPPV vs oxygen therapy

Duration of ICU stay · adults (aged > 17 years) with acute respiratory failure after upper abdominal surgery

It is very uncertain whether noninvasive positive pressure ventilation (NPPV) changes ICU length of stay compared with oxygen therapy (very low certainty).

1 finding from 1 review