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Evidence found and GRADE certainty

3,703 questions · 3,824 findings · 858 reviews

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No studies found 573 · 15%GRADE not reported 383 · 10%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Papilla base incision (PBI) vs Complete papilla mobilisation (sulcular incision)

Postoperative pain (VAS 0-100) - 2 days · People requiring retreatment of periapical lesions (failed root canal therapy)

Papilla base incision (PBI) showed no clear difference in postoperative pain (VAS 0-100) - 2 days compared with complete papilla mobilisation (sulcular incision); GRADE not reported.

1 finding from 1 review

Papilla base incision (PBI) vs Complete papilla mobilisation (sulcular incision)

Postoperative pain (VAS 0-100) - 1 day · People requiring retreatment of periapical lesions (failed root canal therapy)

It is very uncertain whether papilla base incision (PBI) changes postoperative pain (VAS 0-100) - 1 day compared with complete papilla mobilisation (sulcular incision) (very low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Daytime symptom: thirstiness in the morning (questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

Oral appliance or functional orthopaedic appliance showed no clear difference in daytime symptom: thirstiness in the morning (questionnaire) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Tiredness · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: tiredness (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Daytime symptom: sleepiness (Brouillette questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: sleepiness (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Irritability · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: irritability (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Daytime symptom: morning headache (Brouillette questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: morning headache (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Mineral trioxide aggregate (MTA) root-end filling vs Gutta-percha smoothing (orthograde GP root filling)

Postoperative pain (VAS 0-100) - 1 day · People requiring retreatment of periapical lesions (failed root canal therapy)

Mineral trioxide aggregate (MTA) root-end filling showed no clear difference in postoperative pain (VAS 0-100) - 1 day compared with gutta-percha smoothing (orthograde GP root filling) (low certainty).

1 finding from 1 review

Vitamin A vs no supplementation

Chronic lung disease · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A showed no clear difference in chronic lung disease (oxygen use at 28 days in survivors) compared with no supplementation (moderate certainty).

1 finding from 1 review

Vitamin A vs no supplementation

Death or chronic lung disease · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A probably leads to lower death or chronic lung disease (oxygen use at 28 days) compared with no supplementation (moderate certainty).

1 finding from 1 review

Intervention not reported

Early mortality (90 days) · patients with diffuse emphysema

The intervention probably leads to higher early mortality (90 days) (moderate certainty).

1 finding from 1 review

Intervention not reported

Live birth ‐ Clomiphene citrate 5 days versus clomiphene citrate 10 days · ovulation induction in polycystic ovarian syndrome

The intervention may leads to lower live birth ‐ Clomiphene citrate 5 days versus clomiphene citrate 10… (low certainty).

1 finding from 1 review

Intervention not reported

Clinical pregnancy ‐ Clomiphene citrate 5 days versus clomiphene citrate 10 days · ovulation induction in polycystic ovarian syndrome

The intervention may leads to lower clinical pregnancy ‐ Clomiphene citrate 5 days versus clomiphene… (low certainty).

1 finding from 1 review