Findings

What do systematic reviews say?

4,587 questions · 5,761 findings · 495 reviews

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No studies found 1,011 · 17.5%GRADE not reported 1,797 · 31.2%Very low 1,100 · 19.1%Low 1,052 · 18.3%Moderate 649 · 11.3%High 152 · 2.6%

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MDAC + hospital intervention vs SDAC + hospital intervention

Drug absorption: cardenolide: AUC (µg × L/h) · first aid in patients with acute oral poisoning (carbamazepine, yellow oleander, or combinations of different drugs)

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 64 participants
Very low

SDAC vs no intervention

Incidence of adverse events · first aid in patients with acute oral poisoning (paracetamol or not specified)

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 476 participants
Very low

MDAC + hospital intervention vs SDAC + hospital intervention

Hospitalization · first aid in patients with acute oral poisoning (carbamazepine, yellow oleander, or combinations of different drugs)

The review found no eligible studies for this question.

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

MDAC + hospital intervention vs SDAC + hospital intervention

Incidence of admissions to the ICU · first aid in patients with acute oral poisoning (carbamazepine, yellow oleander, or combinations of different drugs)

MDAC + hospital intervention may leads to lower incidence of ICU admission compared with SDAC + hospital intervention (low certainty).

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
RR 0.31 [0.12, 0.83]
1 study · 401 participants
Low

SDAC vs syrup of ipecac

Incidence of mortality · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)

The review found no eligible studies for this question.

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SDAC vs syrup of ipecac

Incidence of adverse events · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)

It is very uncertain whether SDAC changes incidence of adverse events compared with syrup of ipecac (very low certainty).

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
RR 1.24 [0.26, 5.83]
1 study · 34 participants
Very low

SDAC vs syrup of ipecac

Incidence and severity of symptoms of poisoning: level of coma · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

SDAC vs syrup of ipecac

Duration of toxic symptoms · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)

The review found no eligible studies for this question.

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SDAC vs syrup of ipecac

Drug absorption · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)

The review found no eligible studies for this question.

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SDAC vs syrup of ipecac

Hospitalization · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)

The review found no eligible studies for this question.

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

SDAC vs syrup of ipecac

Incidence of admissions to the ICU · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)

The review found no eligible studies for this question.

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

MDAC + hospital intervention vs hospital intervention

Incidence of mortality · first aid in patients with acute oral poisoning (benzodiazepines, yellow oleander or combinations of different drugs)

MDAC + hospital intervention showed no clear difference in incidence of mortality compared with hospital intervention (low certainty).

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
RR 0.94 [0.72, 1.22]
1 study · 3085 participants
Low

SDAC vs no intervention

Incidence and severity of symptoms of poisoning: incidence of clinical deterioration during stay in the hospital · first aid in patients with acute oral poisoning (paracetamol or not specified)

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 451 participants
Very low

MDAC + hospital intervention vs hospital intervention

Incidence of adverse events · first aid in patients with acute oral poisoning (benzodiazepines, yellow oleander or combinations of different drugs)

MDAC + hospital intervention showed no clear difference in incidence of adverse events compared with hospital intervention (low certainty).

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
RR 1.02 [0.52, 1.98]
1 study · 3085 participants
Low

MDAC + hospital intervention vs hospital intervention

Incidence and severity of symptoms of poisoning: incidence of need for intubation · first aid in patients with acute oral poisoning (benzodiazepines, yellow oleander or combinations of different drugs)

MDAC + hospital intervention showed no clear difference in incidence and severity of symptoms of poisoning: incidence of need… compared with hospital intervention (low certainty).

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
RR 0.97 [0.71, 1.33]
1 study · 3085 participants
Low

MDAC + hospital intervention vs hospital intervention

Duration of intubation · first aid in patients with acute oral poisoning (benzodiazepines, yellow oleander or combinations of different drugs)

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Low

MDAC + hospital intervention vs hospital intervention

Drug absorption: cardenolide: AUC (µg/L × h) · first aid in patients with acute oral poisoning (benzodiazepines, yellow oleander or combinations of different drugs)

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 76 participants
Very low

MDAC + hospital intervention vs hospital intervention

Hospitalization · first aid in patients with acute oral poisoning (benzodiazepines, yellow oleander or combinations of different drugs)

The review found no eligible studies for this question.

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

MDAC + hospital intervention vs hospital intervention

Incidence of admissions to the ICU · first aid in patients with acute oral poisoning (benzodiazepines, yellow oleander or combinations of different drugs)

The review found no eligible studies for this question.

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Syrup of ipecac vs no intervention

Incidence of mortality · first aid in patients with acute oral poisoning (toxic berries)

The review found no eligible studies for this question.

1 finding from 1 review

First aid interventions by laypeople for acute oral poisoning 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found