Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,539 questions · 2,602 findings · 424 reviews · Headline outcomes only

No studies found 572 · 22%GRADE not reported 189 · 7.3%Very low 527 · 20.3%Low 685 · 26.3%Moderate 514 · 19.8%High 115 · 4.4%

Tibolone vs combined HT

Breast cancer; women without previous breast cancer (all doses) · postmenopausal women with or without vasomotor symptoms

It is very uncertain whether tibolone changes breast cancer; women without previous breast cancer (all doses) compared with combined HT (very low certainty).

1 finding from 1 review

Tibolone vs placebo

Breast cancer; women without previous breast cancer (all doses) · postmenopausal women with or without vasomotor symptoms

It is very uncertain whether tibolone changes breast cancer; women without previous breast cancer (all doses) compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Behavioural outcome: immunisation rate ATCS Plus, IVR, unidirectional versus no calls, letters, usual care at median · participants at risk of under‐immunisation (children, adolescents and adults)

The intervention probably leads to higher behavioural outcome: immunisation rate ATCS Plus, IVR,… (moderate certainty).

1 finding from 1 review

Intervention not reported

Behavioural outcome: breast cancer screening Multimodal/complex intervention versus usual care at 12 months · participants at risk for breast, colorectal or cervical cancer; or osteoporosis

The intervention leads to higher behavioural outcome: breast cancer screening Multimodal/complex… (high certainty).

1 finding from 1 review

Intervention not reported

Behavioural outcome: breast cancer screening IVR versus enhanced usual care at median · participants at risk for breast, colorectal or cervical cancer; or osteoporosis

The intervention showed no clear difference in behavioural outcome: breast cancer screening IVR versus enhanced… (moderate certainty).

1 finding from 1 review