Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,097 questions · 3,266 findings · 631 reviews

No studies found 430 · 13.2%GRADE not reported 193 · 5.9%Very low 995 · 30.5%Low 904 · 27.7%Moderate 591 · 18.1%High 153 · 4.7%

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Attitudes toward the duty to report child abuse and neglect Measured by: professionals’ self‐reported attitudes towards the duty to report child abuse and neglect Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Number of reported cases of child abuse and neglect (professionals' self‐report, hypothetical vignette cases) Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Number of reported cases of child abuse and neglect (official records of reports made to child protection authorities) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Quality of reported cases of child abuse and neglect (official records of reports made to child protection authorities) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Adverse events · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Knowledge of reporting duty, processes, and procedures Measured by: professionals' self‐reported knowledge of jurisdictional or institutional reporting duties, or both Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Knowledge of core concepts in child abuse and neglect (all forms) Measured by: professionals' self‐reported knowledge of all forms of child abuse and neglect (general measure) Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Knowledge of core concepts in child abuse and neglect (child sexual abuse only) Measured by: professionals' self‐reported knowledge of child sexual abuse (specific measure) Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Skill in distinguishing between reportable and non‐reportable child abuse and neglect cases Measured by: professionals’ performance on simulated cases scored by trained and blinded expert panel Time of outcome assessment: short term (postintervent... · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

MDA vs no MDA

Parasitaemia prevalence · People of all ages living in an area with moderate to high endemicity of P falciparum malaria (≥ 10% prevalence)

MDA showed no clear difference in parasitaemia prevalence compared with no MDA (low certainty).

1 finding from 1 review

MDA vs no MDA

Parasitaemia incidence · People of all ages living in an area with moderate to high endemicity of P falciparum malaria (≥ 10% prevalence)

MDA probably leads to lower parasitaemia incidence compared with no MDA (moderate certainty).

1 finding from 1 review

MDA vs no MDA

Confirmed malaria illness incidence · People of all ages living in an area with moderate to high endemicity of P falciparum malaria (≥ 10% prevalence)

MDA showed no clear difference in confirmed malaria illness incidence compared with no MDA (low certainty).

1 finding from 1 review

Gemcitabine vs BCG

Time to recurrence · participants with recurrent (1‐course BCG failure) high‐risk non‐muscle invasive bladder cancer (49 men, 31 women)Country: Italy

Gemcitabine may leads to lower time to recurrence compared with BCG (low certainty).

1 finding from 1 review

Gemcitabine vs BCG

Time to progression · participants with recurrent (1‐course BCG failure) high‐risk non‐muscle invasive bladder cancer (49 men, 31 women)Country: Italy

Gemcitabine may leads to lower time to progression compared with BCG (low certainty).

1 finding from 1 review

Gemcitabine vs BCG

Adverse events grade 3 to 5 Range of · participants with recurrent (1‐course BCG failure) high‐risk non‐muscle invasive bladder cancer (49 men, 31 women)Country: Italy

It is very uncertain whether gemcitabine changes grade III–V adverse events compared with BCG (very low certainty).

1 finding from 1 review

Gemcitabine vs BCG

Time to death from bladder cancer · participants with recurrent (1‐course BCG failure) high‐risk non‐muscle invasive bladder cancer (49 men, 31 women)Country: Italy

It is very uncertain whether gemcitabine changes time to death from bladder cancer compared with BCG (very low certainty).

1 finding from 1 review

Gemcitabine vs BCG

Time to death from any cause · participants with recurrent (1‐course BCG failure) high‐risk non‐muscle invasive bladder cancer (49 men, 31 women)Country: Italy

The review found no eligible studies for this question.

1 finding from 1 review

Gemcitabine vs BCG

Adverse events: grade 1 to 2 · participants with recurrent (1‐course BCG failure) high‐risk non‐muscle invasive bladder cancer (49 men, 31 women)Country: Italy

It is very uncertain whether gemcitabine changes grade I or II adverse events compared with BCG (very low certainty).

1 finding from 1 review

Gemcitabine vs BCG

Disease‐specific quality of life · participants with recurrent (1‐course BCG failure) high‐risk non‐muscle invasive bladder cancer (49 men, 31 women)Country: Italy

The review found no eligible studies for this question.

1 finding from 1 review