Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,320 questions · 4,561 findings · 388 reviews

No studies found 1,138 · 25%GRADE not reported 886 · 19.4%Very low 1,014 · 22.2%Low 849 · 18.6%Moderate 543 · 11.9%High 131 · 2.9%

Self‐administered medical abortion vs provider‐administered medical abortion

Ongoing pregnancy · women of reproductive age (15 to 49 years) seeking induced abortion

Self‐administered medical abortion showed no clear difference in ongoing pregnancy – RCTs ( compared with provider‐administered medical abortion (low certainty).

1 finding from 1 review

Self‐administered medical abortion vs provider‐administered medical abortion

Any complication requiring surgical intervention ‐ NRSs ( · women of reproductive age (15 to 49 years) seeking induced abortion

The review found no eligible studies for this question.

2 findings from 1 review

Self‐administered medical abortion vs provider‐administered medical abortion

Ongoing pregnancy ‐ NRSs ( · women of reproductive age (15 to 49 years) seeking induced abortion

It is very uncertain whether self‐administered medical abortion changes ongoing pregnancy ‐ NRSs ( compared with provider‐administered medical abortion (very low certainty).

1 finding from 1 review

NSAIDs vs placebo

Proportion of participants experiencing global improvement % of dichotomized Likert scale · Patients with acute low‐back pain

NSAIDs may leads to higher proportion of participants experiencing global improvement Various… compared with placebo (low certainty).

1 finding from 1 review

NSAIDs vs placebo

Proportion of participants experiencing adverse events · Patients with acute low‐back pain

It is very uncertain whether NSAIDs changes proportion of participants experiencing adverse events compared with placebo (very low certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Urinary continence within 1 week after catheter removal MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Retzius‐sparing RALP probably leads to higher urinary continence within 1 week after catheter removal MCID: 5%… compared with standard RALP (moderate certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Urinary continence 3 months after surgery MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Retzius‐sparing RALP may leads to higher urinary continence 3 months after surgery MCID: 5% absolute difference compared with standard RALP (low certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Serious adverse events · men (ages > 18 years) with clinically localized prostate cancer

It is very uncertain whether retzius‐sparing RALP changes serious adverse events compared with standard RALP (very low certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Urinary continence 12 months after surgery MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Retzius‐sparing RALP showed no clear difference in urinary continence 12 months after surgery MCID: 5% absolute… compared with standard RALP (moderate certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Potency 12 months after surgery MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

It is very uncertain whether retzius‐sparing RALP changes potency 12 months after surgery MCID: 5% absolute difference compared with standard RALP (very low certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Positive surgical margins MCID: 5% absolute difference · men (ages > 18 years) with clinically localized prostate cancer

Retzius‐sparing RALP may leads to higher positive surgical margins MCID: 5% absolute difference compared with standard RALP (low certainty).

1 finding from 1 review

Retzius‐sparing RALP vs standard RALP

Biochemical recurrence‐free survival · men (ages > 18 years) with clinically localized prostate cancer

It is very uncertain whether retzius‐sparing RALP changes biochemical recurrence‐free survival compared with standard RALP (very low certainty).

1 finding from 1 review