Findings

What do systematic reviews say?

2,973 questions · 3,072 findings · 410 reviews · Headline outcomes only

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No studies found 559 · 18.2%GRADE not reported 143 · 4.7%Very low 654 · 21.3%Low 833 · 27.1%Moderate 683 · 22.2%High 200 · 6.5%

Intervention not reported

Video‐assisted HINTS

1 finding from 1 review

Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular syndrome 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 199 participants
Very low

Intervention not reported

Clinical HINTS Plus

1 finding from 1 review

Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular syndrome 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 451 participants
Low

Intervention not reported

Video‐assisted HINTS Plus

1 finding from 1 review

Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular syndrome 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 163 participants
Moderate

Intervention not reported

Secondary objectives for HINTS subcomponents

The review found no eligible studies for this question.

1 finding from 1 review

Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular syndrome 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Nystagmus

1 finding from 1 review

Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular syndrome 2023 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1128 participants
Moderate

Intervention not reported

Test of skew

1 finding from 1 review

Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular syndrome 2023 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1313 participants
Moderate

Inhaled corticosteroids vs placebo

Combined outcome of mortality or BPD at 36 weeks' PMA · preterm infants

It is very uncertain whether inhaled corticosteroids changes combined outcome of mortality or BPD at 36 weeks' PMA compared with placebo (very low certainty).

1 finding from 1 review

Late (≥ 7 days) inhaled corticosteroids to reduce bronchopulmonary dysplasia in preterm infants 2022 · Cochrane Headline outcomes only
RR 1.1 [0.74, 1.63]
1 study · 30 participants
Very low

Inhaled corticosteroids vs placebo

Mortality at 36 weeks' PMA · preterm infants

It is very uncertain whether inhaled corticosteroids changes mortality at 36 weeks' PMA compared with placebo (very low certainty).

1 finding from 1 review

Late (≥ 7 days) inhaled corticosteroids to reduce bronchopulmonary dysplasia in preterm infants 2022 · Cochrane Headline outcomes only
RR 3 [0.35, 25.78]
3 studies · 61 participants
Very low

Inhaled corticosteroids vs placebo

Bronchopulmonary dysplasia/chronic lung disease · preterm infants

It is very uncertain whether inhaled corticosteroids changes BPD at 36 weeks' PMA compared with placebo (very low certainty).

1 finding from 1 review

Late (≥ 7 days) inhaled corticosteroids to reduce bronchopulmonary dysplasia in preterm infants 2022 · Cochrane Headline outcomes only
RR 1 [0.59, 1.7]
1 study · 30 participants
Very low

Inhaled corticosteroids vs placebo

Open‐label use of systemic corticosteroids · preterm infants

It is very uncertain whether inhaled corticosteroids changes open‐label use of systemic corticosteroids compared with placebo (very low certainty).

1 finding from 1 review

Late (≥ 7 days) inhaled corticosteroids to reduce bronchopulmonary dysplasia in preterm infants 2022 · Cochrane Headline outcomes only
RR 0.51 [0.26, 1]
4 studies · 74 participants
Very low

Summary of findings: Inhaled antibiotics vs IV antibiotics

Quality of life perceived change in lifestyle after treatment · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Summary of findings: Inhaled antibiotics vs IV antibiotics

Time off school or work · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

The review found no eligible studies for this question.

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: Inhaled antibiotics vs IV antibiotics

Lung function · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Summary of findings: Inhaled antibiotics vs IV antibiotics

Need for additional IV or oral antibiotics · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

It is very uncertain whether summary of findings: Inhaled antibiotics changes need for additional IV or oral antibiotics compared with IV antibiotics (very low certainty).

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
RR 6.11 [0.33, 111.71]
1 study · 18 participants
Very low

Summary of findings: Inhaled antibiotics vs IV antibiotics

Adverse events · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Summary of findings: Inhaled antibiotics vs IV antibiotics

Microbiology Emergence of resistant organisms · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

Intervention not reported

Index test result · of people with HIV‐negative or unknown HIV status who are considered eligible for systematic screening for tuberculosis disease. Role of…

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
0 participants
GRADE not reported

Intervention not reported

False positives (participants incorrectly classified as having tuberculosis disease) · of people with HIV‐negative or unknown HIV status who are considered eligible for systematic screening for tuberculosis disease. Role of…

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
124 participants
Low

Intervention not reported

Index Test result · of people with HIV‐negative or unknown HIV status who are considered eligible for systematic screening for tuberculosis disease. Role of…

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
0 participants
GRADE not reported

Intervention not reported

True positives (participants with tuberculosis disease) · of people with HIV‐negative or unknown HIV status who are considered eligible for systematic screening for tuberculosis disease. Role of…

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
4 participants
Very low