What do systematic reviews say?

Totally percutaneous vs cut‐down femoral artery access

Totally percutaneous showed no clear difference in short‐term mortality (30‐day or in‐hospital) compared with cut‐down femoral artery access (low certainty).

• Totally percutaneous versus surgical cut‐down femoral artery access for elective bifurcated abdominal endovascular… 2023 · Cochrane Headline outcomes only
  RR 1.5 [0.06, 36.18]
  2 studies · 181 participants
  Low

Totally percutaneous vs cut‐down femoral artery access

Totally percutaneous showed no clear difference in failure of aneurysm exclusion( compared with cut‐down femoral artery access (moderate certainty).

• Totally percutaneous versus surgical cut‐down femoral artery access for elective bifurcated abdominal endovascular… 2023 · Cochrane Headline outcomes only
  RR 0.17 [0.01, 4.02]
  1 study · 151 participants
  Moderate

Totally percutaneous vs cut‐down femoral artery access

Totally percutaneous showed no clear difference in wound infection (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

• Totally percutaneous versus surgical cut‐down femoral artery access for elective bifurcated abdominal endovascular… 2023 · Cochrane Headline outcomes only
  RR 0.18 [0.01, 3.59]
  3 studies · 318 participants
  Moderate

Totally percutaneous vs cut‐down femoral artery access

Totally percutaneous showed no clear difference in major complications (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

• Totally percutaneous versus surgical cut‐down femoral artery access for elective bifurcated abdominal endovascular… 2023 · Cochrane Headline outcomes only
  RR 1.21 [0.61, 2.41]
  3 studies · 318 participants
  Moderate

Totally percutaneous vs cut‐down femoral artery access

Totally percutaneous showed no clear difference in medium‐ to long‐term complications( compared with cut‐down femoral artery access (moderate certainty).

• Totally percutaneous versus surgical cut‐down femoral artery access for elective bifurcated abdominal endovascular… 2023 · Cochrane Headline outcomes only
  RR 0.82 [0.25, 2.65]
  1 study · 135 participants
  Moderate

Totally percutaneous vs cut‐down femoral artery access

Totally percutaneous showed no clear difference in bleeding complications (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

• Totally percutaneous versus surgical cut‐down femoral artery access for elective bifurcated abdominal endovascular… 2023 · Cochrane Headline outcomes only
  RR 1.02 [0.29, 3.64]
  2 studies · 181 participants
  Moderate

Totally percutaneous vs cut‐down femoral artery access

• Totally percutaneous versus surgical cut‐down femoral artery access for elective bifurcated abdominal endovascular… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 318 participants
  Low

Superselective neck dissection vs Elective selective neck dissection

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
  Adverse events: no adverse events reported; 72 participants (2 RCTs).
  2 studies · 72 participants
  Very low

Superselective neck dissection vs Elective selective neck dissection

The review found no eligible studies for this question.

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
  Total mortality: not reported.
  0 studies
  No studies found

Supraomohyoid neck dissection vs Modified radical neck dissection

The review found no eligible studies for this question.

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
  Disease-free survival: not reported (Guo 2014 reported disease-specific survival, not a review outcome).
  0 studies
  No studies found

Sentinel node biopsy (neck dissection only if biopsy positive) vs Elective neck dissection

Sentinel node biopsy (neck dissection only if biopsy positive) showed no clear difference in total mortality compared with elective neck dissection (low certainty).

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes

  3 years
  HR 1.00 [0.90, 1.11]
  1 study · 279 participants
  Low

Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy)

The review found no eligible studies for this question.

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes

  oral cavity
  Recurrence: not reported for the oral cancer subgroup (Iyer 2015).
  0 studies
  No studies found

Superselective neck dissection vs Elective selective neck dissection

The review found no eligible studies for this question.

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
  Recurrence: outcome not reported in a usable way in either study.
  0 studies
  No studies found

Supraomohyoid neck dissection vs Modified radical neck dissection

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
  Adverse events: significant difference in complication rates, lower for supraomohyoid (SOND 13.0% vs MRND 21.9%, P=0.040). UW-QOL at 1 year: supraomohyoid superior in pain relief (78.8% vs 75.2%, P=0.013) and shoulder…
  1 study · 332 participants
  Very low

PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy

PET-CT following chemoradiotherapy (neck dissection only if… showed no clear difference in locoregional recurrence compared with planned neck dissection before or after chemoradiotherapy (moderate certainty).

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes

  3 years
  HR 1.00 [0.94, 1.06]
  1 study · 564 participants
  Moderate

Elective neck dissection (at time of primary tumour resection) vs Therapeutic (delayed) neck dissection

Elective neck dissection (at time of primary tumour resection) probably leads to lower locoregional recurrence compared with therapeutic (delayed) neck dissection (moderate certainty).

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes

  3 years
  HR 0.58 [0.43, 0.78]
  4 studies · 458 participants
  Moderate

Supraomohyoid neck dissection vs Modified radical neck dissection

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
  Total mortality: reported but not usable (Guo 2014: during follow-up 113/322 (35.1%) died; SOND 53, MRND 60). No GRADE rating.
  1 study
  GRADE not reported

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

It is very uncertain whether elective radical (comprehensive) neck dissection changes recurrence compared with elective selective neck dissection (very low certainty).

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes

  5 years
  RR 1.21 [0.63, 2.33]
  1 study · 143 participants
  Very low

Supraomohyoid neck dissection vs Modified radical neck dissection

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
  Recurrence: reported but not usable (variable follow-up) (Guo 2014).
  1 study
  GRADE not reported

Elective neck dissection (at time of primary tumour resection) vs Therapeutic (delayed) neck dissection

Elective neck dissection (at time of primary tumour resection) probably leads to lower mortality (overall survival) compared with therapeutic (delayed) neck dissection (moderate certainty).

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes

  3 years
  HR 0.64 [0.50, 0.83]
  4 studies · 883 participants
  Moderate