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What do systematic reviews say?

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Evidence found and GRADE certainty

4,749 questions · 14,273 findings · 834 reviews

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No studies found 3,655 · 25.6%GRADE not reported 2,115 · 14.8%Very low 3,646 · 25.5%Low 3,034 · 21.3%Moderate 1,503 · 10.5%High 320 · 2.2%

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Lifestyle interventions vs placebo or usual care

Overall survival (24 months) · weight reduction in obesity to improve survival in women with endometrial cancer

It is very uncertain whether summary of findings table ‐ Lifestyle intervention changes overall survival (24 months) compared with usual care compared to placebo (very low certainty).

1 finding from 1 review

Lifestyle interventions vs placebo or usual care

Adverse events – musculoskeletal · weight reduction in obesity to improve survival in women with endometrial cancer

It is very uncertain whether summary of findings table ‐ Lifestyle intervention changes adverse events – musculoskeletal compared with usual care compared to placebo (very low certainty).

1 finding from 1 review

Lifestyle interventions vs placebo or usual care

Cardiovascular and metabolic event frequency (12 months) (Number of strokes, myocardial infarctions and hospitalisations for heart failure) · weight reduction in obesity to improve survival in women with endometrial cancer

Summary of findings table ‐ Lifestyle intervention showed no clear difference in cardiovascular and metabolic event frequency (6 months) compared with usual care compared to placebo (low certainty).

1 finding from 1 review

Intervention not reported

Quality of care: adherence to evidence‐based recommendations during hospital admission · health professionals providing care to patients with stroke

It is very uncertain whether the intervention changes quality of care: adherence to evidence‐based recommendations during… (very low certainty).

1 finding from 1 review

Intervention not reported

Quality of care: proportion of patients with ischaemic stroke who receive thrombolysis (first 24 hours of admission) · health professionals providing care to patients with stroke

The intervention showed no clear difference in quality of care: proportion of patients with ischaemic stroke who… (moderate certainty).

1 finding from 1 review

Intervention not reported

Quality of care: proportion of patients who receive a swallow screen within 24 hours of admission · health professionals providing care to patients with stroke

The intervention probably leads to higher quality of care: proportion of patients who receive a swallow screen… (moderate certainty).

1 finding from 1 review

Intervention not reported

Patient outcome: death, disability or dependency at 90 days · health professionals providing care to patients with stroke

The intervention showed no clear difference in patient outcome: death, disability or dependency at 90 days (moderate certainty).

1 finding from 1 review