Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Summary of findings table ‐ Rifampin/rifampicin vs placebo

Risk for at least one adverse event per patient · participants with cholestatic pruritus (CP)

It is very uncertain whether summary of findings table ‐ Rifampin/rifampicin changes risk for at least one adverse event per patient compared with placebo (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Off‐midline closure vs tension‐free midline closure

Wound infection · pilonidal sinus

It is very uncertain whether summary of findings table ‐ Off‐midline closure changes wound infection compared with tension‐free midline closure (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Off‐midline closure vs tension‐free midline closure

Wound dehiscence · pilonidal sinus

It is very uncertain whether summary of findings table ‐ Off‐midline closure changes wound dehiscence compared with tension‐free midline closure (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Off‐midline closure vs conventional midline closure

Proportion of wounds healed · pilonidal sinus

It is very uncertain whether summary of findings table ‐ Off‐midline closure changes proportion of wounds healed compared with conventional midline closure (very low certainty).

1 finding from 1 review