DMFT/DMFS index (dental caries experience) · Children aged 0-12 years in Ireland
The single Irish study showed lower DMFT/S with OHPP (OR 0.52, 95% CI 0.45 to 0.61; ungraded, single study).
1 finding from 1 review
Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
The review found no eligible studies for this question.
1 finding from 1 review
Caries increment, tooth index D(M)FT · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
1055 to 1100 ppm F toothpaste showed no clear difference in caries increment, tooth index d(m)ft compared with 500 to 550 ppm F toothpaste (low certainty).
1 finding from 1 review
DMFT/DMFS index (dental caries experience) · Children aged 0-12 years in Japan
The single Japanese study yielded a degenerate estimate of OR 0.00 (95% CI 0.00 to 0.00; ungraded, single study).
1 finding from 1 review
Gingival bleeding (various bleeding indices) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
It is very uncertain whether 1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily changes gingival bleeding index (mean change from baseline) compared with 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily (very low certainty).
1 finding from 1 review
Gingivitis · Adults, 16 years and older (dentate)
It is very uncertain whether rubber/elastomeric cleaning stick plus toothbrushing changes gingivitis (proportion of bleeding sites) compared with interdental brushing plus toothbrushing (very low certainty).
2 findings from 1 review
Adverse effects of toothpaste · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects (including quality of life) · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
1 finding from 1 review
This comparison was only made in 1 study which reported no serious adverse events associated with HBO therapy. Quality of life measures (oral status, functioning, satisfaction) showed emotional functioning and pain…
1 study · 26 participants
Very low
Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
1000 to 1250 ppm F toothpaste showed no clear difference in caries increment, tooth index D(M)FT compared with 250 ppm F toothpaste (low certainty).
1 finding from 1 review
SMD -0.15 [-0.31, 0.0]
3 studies
Low
Adverse effects · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
1 finding from 1 review
Adverse effects were an outcome of interest in the study conducting this comparison, however no mention was made of the presence or absence of any adverse events
1 study · 74 participants
Very low
Adverse effects of toothpaste · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
1 finding from 1 review
Adverse effects of toothpaste: not estimable. "There were no reports on adverse effects, but some children complained about the taste of the dentifrice" (Cardoso 2014); 195 participants (1 RCT); low-certainty.
1 study · 195 participants
Low
Dental caries · Children aged 5-7 years (early school-age)
In early school-age children (5-7 y) from heavily contaminated areas, individual studies gave conflicting DMFT/dmft differences (some favouring exposed, some non-exposed); the review did not pool them (ungraded).
4 findings from 1 review
A systematic review of the caries prevalence among children living in Chernobyl fallout countries. 2019 All outcomesChernobyl fallout areas, Eastern Europe (Ukraine, Belarus, Russian Federation) · heavy contamination
WMD -0.81 [-1.06, -0.56]
1 study · 80 participants
GRADE not reported
A systematic review of the caries prevalence among children living in Chernobyl fallout countries. 2019 All outcomesChernobyl fallout areas, Eastern Europe (Ukraine, Belarus, Russian Federation) · heavy contamination
WMD -1.03 [-1.36, -0.70]
1 study · 78 participants
GRADE not reported
A systematic review of the caries prevalence among children living in Chernobyl fallout countries. 2019 All outcomesChernobyl fallout areas, Eastern Europe (Ukraine, Belarus, Russian Federation) · heavy contamination
WMD 1.75 [1.73, 1.77]
1 study · 1474 participants
GRADE not reported
Show 1 more finding
White spot lesion index (mean change from baseline) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
It is very uncertain whether 1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily changes white spot lesion index (mean change from baseline) compared with 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily (very low certainty).
1 finding from 1 review
Caries increment, surface index D(M)FS · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
1055 to 1100 ppm F toothpaste showed no clear difference in caries increment, surface index d(m)fs compared with 500 to 550 ppm F toothpaste (moderate certainty).
1 finding from 1 review
Plaque · Adults, 16 years and older (dentate)
Oral irrigation plus toothbrushing showed no clear difference in plaque compared with toothbrushing alone (low certainty).
1 finding from 1 review
Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
1700 to 2200 ppm F toothpaste may leads to lower caries increment, surface index D(M)FS compared with non-fluoride (0 ppm F) placebo toothpaste (low certainty).
1 finding from 1 review
SMD -0.32 [-0.41, -0.22]
Studies not reported
Low
Proportion developing new caries · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
1450 ppm F toothpaste probably leads to lower proportion developing new caries compared with 440 ppm F toothpaste (moderate certainty).
1 finding from 1 review
Interproximal caries · Adults, 16 years and older (dentate)
The review found no eligible studies for this question.
1 finding from 1 review
Caries increment, surface index D(M)FS · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
1500 ppm F toothpaste probably leads to lower caries increment, surface index d(m)fs compared with non-fluoride (0 ppm F) placebo toothpaste (moderate certainty).
1 finding from 1 review
Change in haemoglobin level from baseline · People with haemophilia (A or B) undergoing minor oral surgery or dental extractions
1 finding from 1 review
Mean fall in haemoglobin. Forbes (TXA): 1.4 g/100 mL (placebo) vs 0.3 g/100 mL (TXA). Walsh (EACA): 6.3% (placebo, both centres) vs 3.9% and 3.7% (EACA, centres 1 and 2); differences not significant. Reported in…
2 studies · 59 participants
GRADE not reported