Findings

What do systematic reviews say?

2,805 questions · 2,912 findings · 307 reviews · Headline outcomes only

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No studies found 706 · 24.2%GRADE not reported 133 · 4.6%Very low 786 · 27%Low 696 · 23.9%Moderate 474 · 16.3%High 117 · 4%

HALOPERIDOL vs placebo

Number of delirium ‐ and coma‐free days (within 28 days) measured by CAM‐ICU or ICDSC · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…

1 finding from 1 review

Interventions for preventing intensive care unit delirium in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1580 participants
Moderate

HALOPERIDOL vs placebo

Ventilator‐free days up to day 28 · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…

1 finding from 1 review

Interventions for preventing intensive care unit delirium in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1439 participants
High

HALOPERIDOL vs placebo

Duration of ICU stay · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…

1 finding from 1 review

Interventions for preventing intensive care unit delirium in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1580 participants
High

HALOPERIDOL vs placebo

Cognitive impairment · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing intensive care unit delirium in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

HALOPERIDOL vs placebo

Adverse events · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…

1 finding from 1 review

Interventions for preventing intensive care unit delirium in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1580 participants
Moderate

Intervention not reported

Tobacco use · children and young people aged 0 to 18 years

The intervention showed no clear difference in tobacco use (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 1.28 [0.75, 2.19]
2 studies · 521 participants
Moderate

Intervention not reported

Alcohol use · children and young people aged 0 to 18 years

The intervention showed no clear difference in alcohol use (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 0.8 [0.58, 1.11]
4 studies · 1911 participants
Moderate

Intervention not reported

Cannabis use · children and young people aged 0 to 18 years

The intervention showed no clear difference in cannabis use (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 0.69 [0.46, 1.04]
2 studies · 362 participants
Moderate

Intervention not reported

Illicit drug use · children and young people aged 0 to 18 years

The review found no eligible studies for this question.

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Antisocial behaviour · children and young people aged 0 to 18 years

The intervention showed no clear difference in antisocial behaviour (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 1.02 [0.62, 1.69]
1 study · 200 participants
Moderate

Intervention not reported

Sexual risk behaviour · children and young people aged 0 to 18 years

The intervention showed no clear difference in sexual risk behaviour (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 0.42 [0.14, 1.25]
1 study · 162 participants
Moderate

Intervention not reported

Physical activity · children and young people aged 0 to 18 years

The intervention showed no clear difference in physical activity (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 1.11 [0.74, 1.67]
2 studies · 1530 participants
Moderate

Intervention not reported

Tobacco use · children and young people aged 0 to 18 years

The intervention showed no clear difference in tobacco use (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 0.78 [0.4, 1.53]
2 studies · 313 participants
Moderate

Intervention not reported

Alcohol use · children and young people aged 0 to 18 years

The intervention showed no clear difference in alcohol use (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 0.83 [0.47, 1.46]
3 studies · 417 participants
Moderate

Intervention not reported

Cannabis use · children and young people aged 0 to 18 years

The intervention showed no clear difference in cannabis use (low certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 1.02 [0.52, 2.02]
3 studies · 380 participants
Low

Intervention not reported

Illicit drug use · children and young people aged 0 to 18 years

The intervention showed no clear difference in illicit drug use (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 0.74 [0.42, 1.31]
1 study · 69 participants
Moderate

Intervention not reported

Alcohol use · children and young people aged 0 to 18 years

The intervention showed no clear difference in alcohol use (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 1.02 [0.8, 1.31]
4 studies · 1204 participants
Moderate

Intervention not reported

Antisocial behaviour · children and young people aged 0 to 18 years

The intervention showed no clear difference in antisocial behaviour (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 0.84 [0.57, 1.24]
5 studies · 772 participants
Moderate

Intervention not reported

Sexual risk behaviour · children and young people aged 0 to 18 years

The intervention showed no clear difference in sexual risk behaviour (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 0.89 [0.55, 1.44]
3 studies · 371 participants
Moderate

Intervention not reported

Physical activity · children and young people aged 0 to 18 years

The intervention showed no clear difference in physical activity (moderate certainty).

1 finding from 1 review

Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people 2018 · Cochrane Headline outcomes only
OR 0.72 [0.29, 1.79]
1 study · 61 participants
Moderate