What do systematic reviews say?

Case management vs usual care

Case management showed no clear difference in quality of life (participants) at 12 months compared with usual care (high certainty).

• Case management approaches to home support for people with dementia 2015 · Cochrane Headline outcomes only
  SMD 0.05
  3 studies · 511 participants
  High

Internet‐based interventions vs usual care or no treatment

Internet‐based interventions showed no clear difference in total mortality compared with usual care or no care (low certainty).

• Internet‐based interventions for the secondary prevention of coronary heart disease 2015 · Cochrane Headline outcomes only
  OR 0.27 [0.04, 1.63]
  6 studies · 895 participants
  Low

Internet‐based interventions vs usual care or no treatment

Internet‐based interventions showed no clear difference in revascularisation compared with usual care or no care (low certainty).

• Internet‐based interventions for the secondary prevention of coronary heart disease 2015 · Cochrane Headline outcomes only
  OR 0.69 [0.37, 1.27]
  6 studies · 895 participants
  Low

Internet‐based interventions vs usual care or no treatment

• Internet‐based interventions for the secondary prevention of coronary heart disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 439 participants
  Low

Internet‐based interventions vs usual care or no treatment

• Internet‐based interventions for the secondary prevention of coronary heart disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 437 participants
  Low

Internet‐based interventions vs usual care or no treatment

• Internet‐based interventions for the secondary prevention of coronary heart disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 437 participants
  Low

Internet‐based interventions vs usual care or no treatment

• Internet‐based interventions for the secondary prevention of coronary heart disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 439 participants
  Low

Internet‐based interventions vs usual care or no treatment

• Internet‐based interventions for the secondary prevention of coronary heart disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 623 participants
  Low

Internet‐based interventions vs usual care or no treatment

• Internet‐based interventions for the secondary prevention of coronary heart disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 622 participants
  Low

Goal setting with or without strategies to enhance goal pursuit vs usual care

• Goal setting and strategies to enhance goal pursuit for adults with acquired disability participating in rehabilitation 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 229 participants
  Very low

Goal setting with or without strategies to enhance goal pursuit vs usual care

• Goal setting and strategies to enhance goal pursuit for adults with acquired disability participating in rehabilitation 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 32 participants
  Very low

Goal setting with or without strategies to enhance goal pursuit vs usual care

• Goal setting and strategies to enhance goal pursuit for adults with acquired disability participating in rehabilitation 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 134 participants
  Very low

Goal setting with or without strategies to enhance goal pursuit vs usual care

• Goal setting and strategies to enhance goal pursuit for adults with acquired disability participating in rehabilitation 2015 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 441 participants
  Low

Goal setting with or without strategies to enhance goal pursuit vs usual care

• Goal setting and strategies to enhance goal pursuit for adults with acquired disability participating in rehabilitation 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 201 participants
  Very low

Goal setting with or without strategies to enhance goal pursuit vs usual care

• Goal setting and strategies to enhance goal pursuit for adults with acquired disability participating in rehabilitation 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 277 participants
  Low

Nurse‐led titration vs usual care

Nurse‐led titration leads to lower all‐cause hospital admissions compared with usual care (high certainty).

• Nurse‐led titration of angiotensin converting enzyme inhibitors, beta‐adrenergic blocking agents, and angiotensin… 2015 · Cochrane Headline outcomes only
  RR 0.8 [0.72, 0.88]
  4 studies · 560 participants
  High

Nurse‐led titration vs usual care

Nurse‐led titration probably leads to lower heart failure‐related hospital admissions compared with usual care (moderate certainty).

• Nurse‐led titration of angiotensin converting enzyme inhibitors, beta‐adrenergic blocking agents, and angiotensin… 2015 · Cochrane Headline outcomes only
  RR 0.51 [0.36, 0.72]
  4 studies · 642 participants
  Moderate

Nurse‐led titration vs usual care

Nurse‐led titration probably leads to lower all‐cause mortality compared with usual care (moderate certainty).

• Nurse‐led titration of angiotensin converting enzyme inhibitors, beta‐adrenergic blocking agents, and angiotensin… 2015 · Cochrane Headline outcomes only
  RR 0.66 [0.48, 0.92]
  6 studies · 902 participants
  Moderate

Nurse‐led titration vs usual care

Nurse‐led titration probably leads to lower all‐cause event‐free survival compared with usual care (moderate certainty).

• Nurse‐led titration of angiotensin converting enzyme inhibitors, beta‐adrenergic blocking agents, and angiotensin… 2015 · Cochrane Headline outcomes only
  RR 0.6 [0.46, 0.77]
  3 studies · 370 participants
  Moderate

Nurse‐led titration vs usual care

Nurse‐led titration may leads to higher proportion reaching target dose of medications compared with usual care (low certainty).

• Nurse‐led titration of angiotensin converting enzyme inhibitors, beta‐adrenergic blocking agents, and angiotensin… 2015 · Cochrane Headline outcomes only
  RR 1.99 [1.61, 2.47]
  5 studies · 966 participants
  Low