Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,922 questions · 3,118 findings · 513 reviews

No studies found 574 · 18.4%GRADE not reported 372 · 11.9%Very low 723 · 23.2%Low 854 · 27.4%Moderate 489 · 15.7%High 106 · 3.4%

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Endothelial function · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in endothelial function (forearm blood flow) compared with no treatment (no periodontal treatment); GRADE not reported.

1 finding from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Plasma level of IL-6 (pg/mL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in plasma level of IL-6 (pg/mL) compared with no treatment (no periodontal treatment); GRADE not reported.

3 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Percentage of bleeding on probing (BOP) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… led to lower bleeding on probing (BOP) compared with no treatment (no periodontal treatment); GRADE not reported.

1 finding from 1 review
  • Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
    Long term · People diagnosed with periodontitis and other cardiovascular diseases except hypertension
    MD -36.80 [-46.47, -27.13]
    1 study · 48 participants
    GRADE not reported

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Heart rate · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in heart rate compared with no treatment (no periodontal treatment); GRADE not reported.

1 finding from 1 review

Intervention not reported

Change in the visual field (short term) · participants with glaucoma or intraocular hypertension
1 finding from 1 review

Intervention not reported

Reduction in IOP (short term) · participants with glaucoma or intraocular hypertension
1 finding from 1 review
  • Acupuncture for glaucoma 2020 · Cochrane Headline outcomes only
    no estimate extracted
    3 studies · 137 participants
    Very low

Intervention not reported

Change in visual acuity (short term) · participants with glaucoma or intraocular hypertension
1 finding from 1 review

Intervention not reported

Progression of optic disc damage or nerve fiber layer loss (short term) · participants with glaucoma or intraocular hypertension
1 finding from 1 review

Intervention not reported

Adverse events (short term) · participants with glaucoma or intraocular hypertension
1 finding from 1 review