Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,289 questions · 2,331 findings · 195 reviews · Pregnancy and Childbirth

No studies found 480 · 20.6%GRADE not reported 288 · 12.4%Very low 467 · 20%Low 630 · 27%Moderate 338 · 14.5%High 128 · 5.5%

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Injection site reactions ‐ induration ‐ swelling · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in injection site reactions ‐ induration ‐ swelling compared with saline placebo (moderate certainty).

1 finding from 1 review

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Systemic reactions ‐ fever (oral temperature ≥ 38°C) · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in systemic reactions ‐ fever (oral temperature ≥ 38°C) compared with saline placebo (moderate certainty).

1 finding from 1 review

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Systemic reactions ‐ headache · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in systemic reactions ‐ headache compared with saline placebo (moderate certainty).

1 finding from 1 review

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Systemic reactions ‐ malaise · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in systemic reactions ‐ malaise compared with saline placebo (moderate certainty).

1 finding from 1 review

Local and systemic reactions after administration of Tetanus Diphtheria acelluar Pertussis vaccine vs saline placebo

Systemic reactions ‐ myalgia · patients with local and systemic reactions

Local and systemic reactions after administration of Tetanus… showed no clear difference in systemic reactions ‐ myalgia compared with saline placebo (moderate certainty).

1 finding from 1 review