Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
1700 to 2200 ppm F toothpaste may leads to lower caries increment, tooth index D(M)FT compared with non-fluoride (0 ppm F) placebo toothpaste (low certainty).
1 finding from 1 review
SMD -0.33 [-0.56, -0.11]
Studies not reported
Low
Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
250 ppm F toothpaste may leads to lower caries increment, surface index D(M)FS compared with non-fluoride (0 ppm F) placebo toothpaste (low certainty).
1 finding from 1 review
SMD -0.15 [-0.25, -0.05]
3 studies
Low
Dental caries · Children of mixed ages (mean approximately 12 years; no age separation)
In children of mixed ages from a weakly contaminated area, one study reported higher DMFT/dmft in exposed than non-exposed children; not pooled (ungraded).
1 finding from 1 review
Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
1450 to 1500 ppm F toothpaste may leads to lower caries increment, tooth index D(M)FT compared with 1000 to 1250 ppm F toothpaste (low certainty).
1 finding from 1 review
SMD -0.13 [-0.23, -0.02]
4 studies
Low
Gingivitis · Adults, 16 years and older (dentate)
It is very uncertain whether flossing plus toothbrushing changes gingivitis (proportion of bleeding sites) compared with toothbrushing alone (very low certainty).
2 findings from 1 review
Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
1450 to 1500 ppm F toothpaste showed no clear difference in caries increment, tooth index D(M)FT compared with 440 to 550 ppm F toothpaste (low certainty).
1 finding from 1 review
SMD -0.2 [-0.45, 0.04]
Studies not reported
Low
Adverse effects · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
The review found no eligible studies for this question.
1 finding from 1 review
Antifibrinolytic therapy (tranexamic acid or epsilon aminocaproic acid) vs Placebo, no intervention or usual care (with or without placebo)
Outcome not reported · People with Von Willebrand disease undergoing minor oral surgery or dental extractions
The review found no eligible studies for this question.
1 finding from 1 review
Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
2400 to 2800 ppm F toothpaste showed no clear difference in caries increment, surface index D(M)FS compared with 1700 to 2200 ppm F toothpaste (low certainty).
1 finding from 1 review
SMD -0.09 [-0.2, 0.02]
1 study
Low
Plaque · Adults, 16 years and older (dentate)
It is very uncertain whether rubber/elastomeric cleaning stick plus toothbrushing changes plaque compared with interdental brushing plus toothbrushing (very low certainty).
1 finding from 1 review
Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
1700 to 2200 ppm F toothpaste showed no clear difference in caries increment, surface index D(M)FS compared with 1450 to 1500 ppm F toothpaste (moderate certainty).
1 finding from 1 review
SMD 0.04 [-0.07, 0.15]
Studies not reported
Moderate
Plaque · Adults, 16 years and older (dentate)
It is very uncertain whether wooden cleaning stick plus toothbrushing changes plaque compared with flossing plus toothbrushing (very low certainty).
1 finding from 1 review
Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
2400 to 2800 ppm F toothpaste showed no clear difference in caries increment, tooth index D(M)FT compared with 1450 to 1500 ppm F toothpaste (low certainty).
1 finding from 1 review
SMD 0.0 [-0.16, 0.17]
Studies not reported
Low
Caries increment, tooth index D(M)FT · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
2400 to 2800 ppm F toothpaste may leads to lower caries increment, tooth index D(M)FT compared with 250 ppm F toothpaste (low certainty).
1 finding from 1 review
SMD -0.28 [-0.48, -0.08]
Studies not reported
Low
Side effects · Adults, 16 years and older (dentate)
1 finding from 1 review
Incidence of ORN · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
It is very uncertain whether hyperbaric oxygen therapy (HBO) following extractions changes incidence of ORN compared with perioperative antibiotic prophylaxis (penicillin G) following… (very low certainty).
1 finding from 1 review
Periodontitis (probing pocket depth) · Adults, 16 years and older (dentate)
1 finding from 1 review
Major bleeding, requiring transfusion of packed red blood cells · People with haemophilia (A or B) undergoing minor oral surgery or dental extractions
1 finding from 1 review
Adverse effects of toothpaste · Young children with primary (deciduous) dentition (aged 1 to 6 years at study start)
The review found no eligible studies for this question.
1 finding from 1 review
Side effects · Adults, 16 years and older (dentate)
1 finding from 1 review