Intervention not reported
Milnacipran standard dose RCTs: 2 Participants: 1298 · people with chronic pain Interventions: desvenlafaxine high dose (≥ 50 mg); duloxetine low dose (< 60 mg), standard dose (60 mg), and high…
1 finding from 1 review
no estimate extracted
2 participants
Low
Intervention not reported
Mirtazapine standard dose RCTs: 1 Participants: 422 · people with chronic pain Interventions: desvenlafaxine high dose (≥ 50 mg); duloxetine low dose (< 60 mg), standard dose (60 mg), and high…
1 finding from 1 review
no estimate extracted
1 participants
Low
Intervention not reported
Duloxetine low dose RCTs: 6 Participants: 1116 · people with chronic pain Interventions: desvenlafaxine high dose (≥ 50 mg); duloxetine low dose (< 60 mg), standard dose (60 mg), and high…
1 finding from 1 review
no estimate extracted
6 participants
Moderate
Intervention not reported
Esreboxetine high dose RCTs: 1 Participants: 555 · people with chronic pain Interventions: desvenlafaxine high dose (≥ 50 mg); duloxetine low dose (< 60 mg), standard dose (60 mg), and high…
1 finding from 1 review
no estimate extracted
1 participants
Very low
Progression of non-cavitated enamel caries · 'Healthy' children with caries-free second primary molars, aged 3-5 years (schools and kindergartens, India and China)
The review found no eligible studies for this question.
1 finding from 1 review
Development of >=1 new carious lesion (caries incidence) · 'Healthy' children with caries-free second primary molars, aged 3-5 years (schools and kindergartens, India and China)
1 finding from 1 review
N/A - insufficient quantitative information available; 200 (2 studies). Comments: Due to the methods of data collection, analysis and reporting we were unable to provide any quantitative estimates. Fei 2011 narrative:…
2 studies · 200 participants
Very low
Retention of sealant (complete or partial retention) · 'Healthy' children with caries-free second primary molars, aged 3-5 years (schools and kindergartens, India and China)
1 finding from 1 review
Adverse events · 'Healthy' children with caries-free second primary molars, aged 3-5 years (schools and kindergartens, India and China)
1 finding from 1 review
1 study reported adverse events as some discomfort such as nausea; 1 child experienced a strong gag reflex following the glass ionomer-based sealant while 8 children reported feeling uncomfortable after the fluoride…
1 study · 100 participants
Very low
Diastolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… showed no clear difference in change in diastolic blood pressure (DBP, mmHg) compared with no treatment (no periodontal treatment) (low certainty).
4 findings from 1 review
Show 1 more finding
Clinical attachment level (CAL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… led to lower clinical attachment level (CAL) compared with no treatment (no periodontal treatment); GRADE not reported.
1 finding from 1 review
Systolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… showed no clear difference in change in systolic blood pressure (SBP, mmHg) compared with no treatment (no periodontal treatment) (low certainty).
4 findings from 1 review
Show 1 more finding
Probing pocket depth · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… led to lower pocket probing depth (PPD) compared with no treatment (no periodontal treatment); GRADE not reported.
1 finding from 1 review
Plasma level of hs-CRP (mg/L) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Periodontal treatment (subgingival SRP with or without other… showed no clear difference in plasma level of hs-CRP (mg/L) compared with no treatment (no periodontal treatment); GRADE not reported.
4 findings from 1 review
Show 1 more finding
Adverse events (participants with adverse events or withdrawals due to adverse events) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
1 finding from 1 review
SoF 1 (Adverse effects): Only 1 study reported that 1 participant in the treatment group experienced a myocardial infarction during the study period. 1 study reported no adverse effects. The remaining 2 studies did not…
2 studies · 294 participants
Low
All‐cause mortality · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
It is very uncertain whether band ligation changes all‐cause mortality compared with sham or no intervention (very low certainty).
1 finding from 1 review
Serious adverse events Idiopathic thrombocytopaenic purpura · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
It is very uncertain whether band ligation changes serious adverse events Idiopathic thrombocytopaenic purpura compared with sham or no intervention (very low certainty).
1 finding from 1 review
Health‐related quality of life · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Oesophageal variceal bleeding · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
It is very uncertain whether band ligation changes oesophageal variceal bleeding compared with sham or no intervention (very low certainty).
1 finding from 1 review
Adverse events considered non‐serious · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Combined outcome of proportion of participants with major or critical monitoring findings · clinical trials in all fields of health care
Risk‐based showed no clear difference in combined outcome of proportion of participants with major or… compared with extensive on‐site monitoring (moderate certainty).
1 finding from 1 review