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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

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No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Physical activity as part of self‐management programme vs watchful waiting

Response rate · men with lower urinary tract symptoms secondary to benign prostatic obstruction

It is very uncertain whether physical activity as part of self‐management programme changes response rate compared with watchful waiting (very low certainty).

1 finding from 1 review

Physical activity as part of weight reduction programme vs watchful waiting

Response rate · men with lower urinary tract symptoms secondary to benign prostatic obstruction

It is very uncertain whether physical activity as part of weight reduction programme changes response rate compared with watchful waiting (very low certainty).

1 finding from 1 review

Physical activity as part of weight reduction programme vs watchful waiting

Withdrawals due to adverse events · men with lower urinary tract symptoms secondary to benign prostatic obstruction

It is very uncertain whether physical activity as part of weight reduction programme changes withdrawal due to adverse events compared with watchful waiting (very low certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

All‐cause mortality · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in all‐cause mortality compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Stroke · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in stroke compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Patient readmissions · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in rehospitalisation compared with surgical aortic valve replacement (low certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Myocardial infarction · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in myocardial infarction compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Cardiac mortality · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in cardiac death compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Permanent pacemaker implantation · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation probably leads to higher permanent pacemaker implantation compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review