Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,372 questions · 3,874 findings · 666 reviews

No studies found 431 · 11.1%GRADE not reported 783 · 20.2%Very low 995 · 25.7%Low 909 · 23.5%Moderate 596 · 15.4%High 160 · 4.1%

Hypofractionated radiotherapy vs daily conventionally fractionated radiotherapy

Overall survival for subgroup age 60 years and older glioblastoma · high‐grade glioma

Hypofractionated radiotherapy showed no clear difference in overall survival for subgroup aged ≥ 60 years glioblastoma compared with daily conventionally fractionated radiotherapy (high certainty).

1 finding from 1 review

Procedures: single‐step doffing vs Centers

Contamination with fluorescent · Preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff

It is very uncertain whether procedures: single‐step doffing changes fluorescent contamination compared with centers (very low certainty).

1 finding from 1 review

Procedures: single‐step doffing vs Centers

Bacterial contamination · Preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff

It is very uncertain whether procedures: single‐step doffing changes bacterial contamination compared with centers (very low certainty).

1 finding from 1 review

Dinutuximab‐containing immunotherapy vs usual care

Overall survival (reported as mortality) · People with high‐risk neuroblastoma pre‐treated with autologous haematopoietic stem cell transplantation

Dinutuximab‐containing immunotherapy probably leads to lower overall survival (reported as mortality) compared with standard therapy (moderate certainty).

1 finding from 1 review

Dinutuximab‐containing immunotherapy vs usual care

Treatment‐related mortality ‐ not reported · People with high‐risk neuroblastoma pre‐treated with autologous haematopoietic stem cell transplantation

The review found no eligible studies for this question.

1 finding from 1 review

Dinutuximab‐containing immunotherapy vs usual care

Progression‐free survival ‐ not reported · People with high‐risk neuroblastoma pre‐treated with autologous haematopoietic stem cell transplantation

The review found no eligible studies for this question.

1 finding from 1 review

Dinutuximab‐containing immunotherapy vs usual care

Event‐free survival · People with high‐risk neuroblastoma pre‐treated with autologous haematopoietic stem cell transplantation

Dinutuximab‐containing immunotherapy probably leads to lower event‐free survival (reported as relapse, progressive disease,… compared with standard therapy (moderate certainty).

1 finding from 1 review

Dinutuximab‐containing immunotherapy vs usual care

Late non‐haematological toxicity ‐ not reported · People with high‐risk neuroblastoma pre‐treated with autologous haematopoietic stem cell transplantation

The review found no eligible studies for this question.

1 finding from 1 review

Dinutuximab‐containing immunotherapy vs usual care

Health‐related quality of life ‐ not reported · People with high‐risk neuroblastoma pre‐treated with autologous haematopoietic stem cell transplantation

The review found no eligible studies for this question.

1 finding from 1 review