Findings

What do systematic reviews say?

2,447 questions · 2,590 findings · 266 reviews

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No studies found 699 · 27%GRADE not reported 289 · 11.2%Very low 614 · 23.7%Low 605 · 23.4%Moderate 322 · 12.4%High 61 · 2.4%

Summary of findings: ACBT vs CCPT

FVC (% predicted) Change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
GRADE not reported

Summary of findings: ACBT vs CCPT

Sputum weight (change from baseline) · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: ACBT vs CCPT

Pulmonary exacerbations · adults and children with cystic fibrosis

Summary of findings: ACBT showed no clear difference in number of pulmonary exacerbations compared with CCPT (low certainty).

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
RR 1.64 [0.62, 4.34]
1 study · 63 participants
Low

Summary of findings: ACBT vs PEP mask therapy

Quality of life (change from baseline) in SF‐36 score and CRQ score · adults and children with cystic fibrosis

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Summary of findings: ACBT vs PEP mask therapy

Personal preference · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Active cycle of breathing technique for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Light-cured resin-modified glass ionomer cement vs Resin composite restoration

Secondary caries · Patients requiring dental restoration; deciduous (primary) teeth

In deciduous teeth at 1 year, a single small trial found no difference in secondary caries between RMGIC and resin composite (RR 1.03, 95% CI 0.07-15.81; ungraded).

1 finding from 1 review

Clinical efficacy of bioactive restorative materials in controlling secondary caries: a systematic review and network… 2023 All outcomes
1 year of follow-up · Restorative dentistry clinical settings; primary studies conducted across multiple countries · Resin-modified GIC (CIVMR)
RR 1.03 [0.07, 15.81]
1 study · 71 participants
GRADE not reported

Amalgam (AAG) vs Glass ionomer cement (GIC)

Secondary caries · Patients requiring dental restoration; permanent teeth

Over 2 or more years in permanent teeth, amalgam had a higher risk of secondary caries than GIC (RR 1.79, 95% CI 1.04-3.09; low certainty).

1 finding from 1 review

Clinical efficacy of bioactive restorative materials in controlling secondary caries: a systematic review and network… 2023 All outcomes
2 or more years of follow-up · Restorative dentistry clinical settings; primary studies conducted across multiple countries
RR 1.79 [1.04, 3.09]
7 studies · 390 participants
Low

Glass ionomer cement vs Resin composite restoration

Secondary caries · Patients requiring dental restoration; permanent teeth

Over 2 or more years in permanent teeth, GIC probably reduces secondary caries versus resin composite (RR 0.50, 95% CI 0.28-0.91; moderate certainty).

2 findings from 1 review

Clinical efficacy of bioactive restorative materials in controlling secondary caries: a systematic review and network… 2023 All outcomes
2 or more years of follow-up · Restorative dentistry clinical settings; primary studies conducted across multiple countries
RR 0.50 [0.28, 0.91]
14 studies · 1571 participants
Moderate
Clinical efficacy of bioactive restorative materials in controlling secondary caries: a systematic review and network… 2023 All outcomes
1 year of follow-up · Restorative dentistry clinical settings; primary studies conducted across multiple countries
RR 0.33 [0.10, 1.05]
5 studies · 380 participants
Low

Amalgam (AAG) vs Resin-modified glass ionomer cement (RMGIC)

Secondary caries · Patients requiring dental restoration; deciduous (primary) teeth

Over 2 or more years in deciduous teeth, amalgam probably had a higher risk of secondary caries than RMGIC (RR 2.46, 95% CI 1.42-4.27; moderate certainty).

1 finding from 1 review

Clinical efficacy of bioactive restorative materials in controlling secondary caries: a systematic review and network… 2023 All outcomes
2 or more years of follow-up · Restorative dentistry clinical settings; primary studies conducted across multiple countries
RR 2.46 [1.42, 4.27]
8 studies · 1135 participants
Moderate

Giomer (GIONOMER) vs Resin-modified glass ionomer cement (RMGIC)

Secondary caries · Patients requiring dental restoration; deciduous (primary) teeth

Over 2 or more years in deciduous teeth, the difference in secondary caries between giomer and RMGIC is uncertain (RR 1.66, 95% CI 0.49-5.61; low certainty).

1 finding from 1 review

Clinical efficacy of bioactive restorative materials in controlling secondary caries: a systematic review and network… 2023 All outcomes
2 or more years of follow-up · Restorative dentistry clinical settings; primary studies conducted across multiple countries
RR 1.66 [0.49, 5.61]
1 study · 38 participants
Low

Intervention not reported

Index test result · of people with HIV‐negative or unknown HIV status who are considered eligible for systematic screening for tuberculosis disease. Role of…

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
0 participants
GRADE not reported

Intervention not reported

False positives (participants incorrectly classified as having tuberculosis disease) · of people with HIV‐negative or unknown HIV status who are considered eligible for systematic screening for tuberculosis disease. Role of…

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
124 participants
Low

Intervention not reported

Index Test result · of people with HIV‐negative or unknown HIV status who are considered eligible for systematic screening for tuberculosis disease. Role of…

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
0 participants
GRADE not reported

Intervention not reported

True positives (participants with tuberculosis disease) · of people with HIV‐negative or unknown HIV status who are considered eligible for systematic screening for tuberculosis disease. Role of…

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
4 participants
Very low

Intervention not reported

False negatives (participants incorrectly classified as not having tuberculosis disease) · of people with HIV‐negative or unknown HIV status who are considered eligible for systematic screening for tuberculosis disease. Role of…

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 participants
Very low

Intervention not reported

True negatives (participants without tuberculosis disease) · of people with HIV‐negative or unknown HIV status who are considered eligible for systematic screening for tuberculosis disease. Role of…

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
648 participants
Low

Intervention not reported

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
347 participants
Low

Intervention not reported

Index Test result · of people with HIV‐negative or unknown HIV status who are considered eligible for systematic screening for tuberculosis disease. Role of…

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
0 participants
GRADE not reported

Intervention not reported

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
5 participants
Very low

Intervention not reported

1 finding from 1 review

Symptom‐ and chest‐radiography screening for active pulmonary tuberculosis in HIV‐negative adults and adults with… 2022 · Cochrane Headline outcomes only
no estimate extracted
0 participants
Very low