CAS improvement (decrease) by 2 or more points · thyroid‐associated ophthalmopathy
It is very uncertain whether summary of findings table ‐ Rituximab changes CAS improvement (decrease) by 2 or more points compared with placebo (very low certainty).
1 finding from 1 review
NOSPECS improvement (decrease) by 2 classes or more · thyroid‐associated ophthalmopathy
It is very uncertain whether summary of findings table ‐ Rituximab changes NOSPECS improvement (decrease) by 2 classes or more compared with placebo (very low certainty).
1 finding from 1 review
Quality of life: CFQ‐R respiratory domain: absolute change from baseline · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
1 finding from 1 review
FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
1 finding from 1 review
Growth · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbation frequency · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects of treatment · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
Oral plus nebulised antibiotics showed no clear difference in adverse effects of treatment compared with oral antibiotics plus nebulised placebo (low certainty).
1 finding from 1 review
Eradication of MRSA · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
Oral plus nebulised antibiotics showed no clear difference in eradication of MRSA compared with oral antibiotics plus nebulised placebo (low certainty).
1 finding from 1 review
Time until next positive MRSA isolate (from clinically relevant respiratory culture) · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
50% or greater reduction in seizure frequency · people with drug‐resistant focal epilepsy
Add‐on stiripentol showed no clear difference in ≥ 50% reduction in seizure frequency compared with add‐on placebo (low certainty).
1 finding from 1 review
Seizure freedom · people with drug‐resistant focal epilepsy
Add‐on stiripentol showed no clear difference in seizure freedom compared with add‐on placebo (low certainty).
1 finding from 1 review
≥ 1 adverse effects · people with drug‐resistant focal epilepsy
Add‐on stiripentol may leads to higher ≥ 1 adverse effects compared with add‐on placebo (low certainty).
1 finding from 1 review
Neurological adverse effects · people with drug‐resistant focal epilepsy
Add‐on stiripentol showed no clear difference in neurological adverse effects compared with add‐on placebo (low certainty).
1 finding from 1 review
Gastrointestinal adverse events · people with drug‐resistant focal epilepsy
1 finding from 1 review
Leaving the study early · people with drug‐resistant focal epilepsy
Add‐on stiripentol showed no clear difference in dropouts compared with add‐on placebo (low certainty).
1 finding from 1 review
Quality of life · people with drug‐resistant focal epilepsy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Failure of PDA closure after first course of treatment (assessed by post‐treatment ECHO) · preterm or low birth weight infants with PDA
Early paracetamol may leads to lower failure of PDA closure after first course of treatment (by… compared with placebo/no intervention (low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay · preterm or low birth weight infants with PDA
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Necrotizing enterocolitis during initial hospital stay (by radiological diagnosis) · preterm or low birth weight infants with PDA
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Failure of PDA closure after first course of treatment (assessed by post‐treatment ECHO) · preterm or low birth weight infants with PDA
Late paracetamol showed no clear difference in failure of PDA closure after first course of treatment (assessed by… compared with placebo/no intervention (low certainty).
1 finding from 1 review