Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,231 questions · 3,354 findings · 394 reviews

No studies found 803 · 23.9%GRADE not reported 267 · 8%Very low 757 · 22.6%Low 859 · 25.6%Moderate 486 · 14.5%High 182 · 5.4%

Cervical pull headgear vs Minor interceptive procedures (control)

Lower incisors to mandible (relationship of lower front teeth to the mandible) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Cervical pull headgear showed no clear difference in lower incisors to mandible at 2 years compared with minor interceptive procedures (control); GRADE not reported.

1 finding from 1 review

Systemic (oral) betamethasone vs Topical triamcinolone acetonide paste

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether systemic (oral) betamethasone changes clinical score compared with topical triamcinolone acetonide paste (very low certainty).

1 finding from 1 review

Intralesional betamethasone vs intralesional injections of triamcinolone acetonide

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

Intralesional betamethasone may leads to higher clinical resolution compared with intralesional triamcinolone acetonide (low certainty).

1 finding from 1 review

Intralesional betamethasone vs intralesional injections of triamcinolone acetonide

Clinical score (14 days) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether intralesional betamethasone changes clinical score (14 days) compared with intralesional triamcinolone acetonide (very low certainty).

1 finding from 1 review

Intervention not reported

Any stroke or operative death (five‐year cumulative) · people with carotid stenosis and recent transient ischaemic attacks (TIA) or minor ischaemic strokes in the territory of that artery

The intervention showed no clear difference in any stroke or operative death (five‐year cumulative) (moderate certainty).

1 finding from 1 review

Intervention not reported

Ipsilateral ischaemic stroke, and any operative stroke or death (five‐year cumulative) · people with carotid stenosis and recent transient ischaemic attacks (TIA) or minor ischaemic strokes in the territory of that artery

The intervention showed no clear difference in ipsilateral ischaemic stroke, and any operative stroke or death… (moderate certainty).

1 finding from 1 review

Intervention not reported

Disabling or fatal ipsilateral ischaemic or operative stroke and death (five‐year cumulative) · people with carotid stenosis and recent transient ischaemic attacks (TIA) or minor ischaemic strokes in the territory of that artery

The intervention showed no clear difference in disabling or fatal ipsilateral ischaemic or operative stroke and… (moderate certainty).

1 finding from 1 review