What do systematic reviews say?

2,261 questions · 2,280 findings · 114 reviews · Cystic Fibrosis and Genetic Disorders

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No studies found 856 · 37.5%GRADE not reported 58 · 2.5%Very low 550 · 24.1%Low 502 · 22%Moderate 271 · 11.9%High 43 · 1.9%

CCPT vs extrapulmonary mechanical percussion

FEF25–75: rate of decline in FEF25–75 · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 151 participants
Very low

CCPT vs extrapulmonary mechanical percussion

Time to first exacerbation requiring intravenous antibiotics · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 151 participants
Very low

CCPT vs extrapulmonary mechanical percussion

QoL · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 151 participants
Very low

CCPT vs extrapulmonary mechanical percussion

Adherence to therapy and individual preference · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 131 participants
Very low

CCPT vs extrapulmonary mechanical percussion

Mucus weight · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CCPT vs ACBT

Annual rate of change in % predicted FEV1 All participants · adults and children with cystic fibrosis

It is very uncertain whether CCPT changes FEV1: annual decline in FEV1 % predicted compared with ACBT (very low certainty).

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
MD 2.8
1 study · 63 participants
Very low

CCPT vs ACBT

Annual rate of change in % predicted FVC Subgroup: Under 13 years of age · adults and children with cystic fibrosis

It is very uncertain whether CCPT changes FVC: annual decline in FVC % predicted compared with ACBT (very low certainty).

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
MD 1.8
1 study · 63 participants
Very low

CCPT vs ACBT

FEF25–75: annual decline in FEF25–75 % predicted · adults and children with cystic fibrosis

It is very uncertain whether CCPT changes FEF25–75: annual decline in FEF25–75 % predicted compared with ACBT (very low certainty).

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
MD 6 [0.55, 11.45]
1 study · 63 participants
Very low

CCPT vs ACBT

Respiratory exacerbations: time to first exacerbation · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CCPT vs ACBT

QoL · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CCPT vs PEP

FVC (% predicted) Change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 169 participants
Very low

CCPT vs ACBT

Adherence to therapy and individual preference · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

CCPT vs ACBT

Mucus weight · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CCPT vs O‐PEP devices

FEV1 % predicted · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 185 participants
Very low

CCPT vs O‐PEP devices

FVC · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 185 participants
Very low

CCPT vs O‐PEP devices

FEF25-75 · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 171 participants
Very low

CCPT vs O‐PEP devices

Respiratory exacerbations: number of respiratory exacerbations per year · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CCPT vs O‐PEP devices

QoL · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 155 participants
Very low

CCPT vs O‐PEP devices

Adherence to therapy and individual preference: TSS score · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 155 participants
Very low

CCPT vs O‐PEP devices

Mucus weight · adults and children with cystic fibrosis

1 finding from 1 review

Conventional chest physiotherapy compared to other airway clearance techniques for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low