Acceptability. Participants experiencing troublesome adverse effects of any nature · adults with acute affective episodes in bipolar disorder
Topiramate as monotherapy showed no clear difference in acceptability with topiramate (12 weeks) Number of participants… compared with an alternative drug (low certainty).
1 finding from 1 review
Response to treatment with topiramate. Number of participants experiencing a 50% reduction or greater in mean score from baseline to end of treatment on symptom rating scales in manic and mixed episodes · adults with acute affective episodes in bipolar disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
> 50% reduction in depressive symptoms · adults with acute affective episodes in bipolar disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Remission · adults with acute affective episodes in bipolar disorder
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Short‐term remission · adults with panic disorder
It is very uncertain whether cognitive behaviour therapy changes short‐term remission ( compared with no treatment (very low certainty).
1 finding from 1 review
Short‐term response ( · adults with panic disorder
It is very uncertain whether cognitive behaviour therapy changes short‐term response ( compared with no treatment (very low certainty).
1 finding from 1 review
Short‐term dropouts ( · adults with panic disorder
It is very uncertain whether cognitive behaviour therapy changes short‐term dropouts ( compared with no treatment (very low certainty).
1 finding from 1 review
Long‐term remission/response · adults with panic disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Short‐term improvement as measured on a continuous scale ( · adults with panic disorder
1 finding from 1 review
Repetition of SH at post‐intervention · self‐harm in children and adolescents (up to 18 years or age)
Comparison 7: Family therapy showed no clear difference in repetition of SH at post‐intervention compared with placebo (moderate certainty).
1 finding from 1 review
Change in depressive symptoms · adults with acute affective episodes in bipolar disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acceptability. Participants experiencing troublesome adverse effects of any nature · adults with acute affective episodes in bipolar disorder
Topiramate as add‐on therapy showed no clear difference in acceptability with topiramate (endpoint: 12 weeks) Number of… compared with placebo (low certainty).
1 finding from 1 review
Response to treatment with topiramate. Number of participants experiencing a 50% reduction or greater in mean score from baseline to end of treatment on symptom rating scales in manic and mixed episodes · adults with acute affective episodes in bipolar disorder
Topiramate as add‐on therapy showed no clear difference in response to treatment with topiramate. Number of participants… compared with placebo (low certainty).
1 finding from 1 review
> 50% reduction in depressive symptoms · adults with acute affective episodes in bipolar disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Remission · adults with acute affective episodes in bipolar disorder
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Efficacy: change in scores from baseline to endpoint (12 weeks) on symptom rating scales in the treatment of manic and mixed episodes Lower scores indicate improvement · adults with acute affective episodes in bipolar disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in depressive symptoms · adults with acute affective episodes in bipolar disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acceptability. Participants experiencing troublesome adverse effects of any nature · adults with acute affective episodes in bipolar disorder
It is very uncertain whether topiramate as add‐on therapy changes acceptability with topiramate (8 weeks) Number of participants… compared with alternative drug (very low certainty).
1 finding from 1 review
Response to treatment with topiramate. Number of participants experiencing a 50% reduction or greater in mean score from baseline to end of treatment on symptom rating scales in manic and mixed episodes · adults with acute affective episodes in bipolar disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
> 50% reduction in depressive symptoms · adults with acute affective episodes in bipolar disorder
It is very uncertain whether topiramate as add‐on therapy changes response to treatment with topiramate. Number of participants… compared with alternative drug (very low certainty).
1 finding from 1 review