Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

227 questions · 239 findings · 17 reviews · Orthodontics

No studies found 54 · 22.6%GRADE not reported 122 · 51%Very low 37 · 15.5%Low 19 · 7.9%Moderate 7 · 2.9%High 0 · 0%

Fixed orthodontic treatment with fixed (multibracket) appliances (exposure) vs None (single-group prevalence/incidence estimate)

Incidence of new ICLs (proportion of subjects developing new lesions) · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new ICLs

About 48% of patients developed new ICLs during fixed orthodontic treatment (pooled incidence 0.48, 95% CI 0.33-0.63; very low certainty; very high heterogeneity).

1 finding from 1 review

Transplantation of other teeth after extraction of the ankylosed teeth vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis

Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…

The review found no eligible studies for this question.

1 finding from 1 review

Fixed prostheses cemented to prepared teeth after extraction or decoronation of the ankylosed teeth vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis

Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…

The review found no eligible studies for this question.

1 finding from 1 review

Implant-supported crowns after extraction or decoronation of the ankylosed teeth vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis

Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…

The review found no eligible studies for this question.

1 finding from 1 review

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Mandibular ramus growth · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
1 finding from 1 review

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Stability of anterior open bite correction (1 year after treatment) · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…

The review found no eligible studies for this question.

1 finding from 1 review

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Reduction or treatment of obstructive sleep apnoea syndrome (OSAS) or upper airway resistance syndrome (UARS) · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…

The review found no eligible studies for this question.

1 finding from 1 review

Removable appliance with palatal crib associated with high-pull chincup vs no treatment

Mandibular ramus growth · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
1 finding from 1 review
  • Orthodontic and orthopaedic treatment for anterior open bite in children 2014 · Cochrane All outcomes
    End of treatment (12 months)
    Cephalometric data (SNA, Co-A, SNB, Ar-Go, Ar.GoMe, Co-Gn, ANB) were reported to be not significantly different between groups; effects were dento-alveolar rather than skeletal. No pooled estimate (Almeida 2005).
    1 study
    GRADE not reported

Removable appliance with palatal crib associated with high-pull chincup vs no treatment

Alteration of hyperdivergent growth pattern · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
1 finding from 1 review
  • Orthodontic and orthopaedic treatment for anterior open bite in children 2014 · Cochrane All outcomes
    End of treatment (12 months)
    The angles (SN.GoGN, SN.PP, NS.Gn) and linear measures (AFA, AFP, AFAI) did not demonstrate significant alterations between groups; interventions did not produce significant changes in the skeletal maxillary or…
    1 study
    GRADE not reported

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Patient satisfaction · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…

The review found no eligible studies for this question.

1 finding from 1 review

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Failure to correct the anterior open bite (open bite not closed) · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…

Frankel's function regulator-4 (FR-4) with lip-seal training led to lower failure to correct the anterior open bite (open bite not closed) compared with no treatment; GRADE not reported.

1 finding from 1 review

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Signs and symptoms of respiratory disease · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…

The review found no eligible studies for this question.

1 finding from 1 review

Repelling-magnet splints vs Bite-blocks

Side effects / adverse effects (unilateral crossbite; transverse problems) · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
1 finding from 1 review
  • Orthodontic and orthopaedic treatment for anterior open bite in children 2014 · Cochrane All outcomes
    About 4 months (treatment interrupted early)
    "After 4 months the open bite was observed to close in the magnet group, but in four out of these ten patients, transverse problems were observed (unilateral crossbite) which led to the interruption of the treatment…
    1 study · 10 participants
    GRADE not reported

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Position of the incisors (upper incisor inclination) · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
1 finding from 1 review
  • Orthodontic and orthopaedic treatment for anterior open bite in children 2014 · Cochrane All outcomes
    End of treatment (about 2 years)
    The angulation of the upper incisors with the palatal plane (1/ANSPNS) decreased on average 0.3 (SD 4.6) degrees in the control group, whereas in the treated group the mean retrusion was 4 (SD 4.6) degrees, P < 0.01.…
    1 study
    GRADE not reported

Frankel's function regulator-4 (FR-4) with lip-seal training vs no treatment

Alteration of hyperdivergent growth pattern · Children and adolescents (over 80% aged 16 years or younger at treatment start) with anterior open bite (lack of vertical overlap or…
1 finding from 1 review
  • Orthodontic and orthopaedic treatment for anterior open bite in children 2014 · Cochrane All outcomes
    End of treatment (about 2 years)
    Multiple cephalometric measures reported (Erbay 1995). Treated group: total anterior facial height (N-Me) +3.9 (SD 1.8) mm, upper anterior facial height (N-ANS) +3.3 (SD 1.2) mm; controls showed significantly greater…
    1 study
    GRADE not reported