Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

338 questions · 369 findings · 33 reviews

No studies found 91 · 24.7%GRADE not reported 68 · 18.4%Very low 125 · 33.9%Low 49 · 13.3%Moderate 32 · 8.7%High 4 · 1.1%

Laser photocoagulation vs no intervention

Worsening of BCVA defined as ≥ 15 ETDRS letters (i.e. 3 ETDRS lines or 0.3 logMAR · people with diabetic macular oedema

Laser photocoagulation probably leads to lower worsening of BCVA defined as ≥ 15 ETDRS letters (i.e. 3 ETDRS lines… compared with no intervention (moderate certainty).

1 finding from 1 review

Laser photocoagulation vs no intervention

Anatomic measures: partial to complete resolution of the macular oedema with stereoscopic fundus photography or biomicroscopy; leakage on fluorescein angiography (IVFA); and, if available, retinal macular thickness with OCT · people with diabetic macular oedema

Laser photocoagulation probably leads to higher anatomic measures: partial to complete resolution of the macular… compared with no intervention (moderate certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Recanalisation or persistence of reflux at 6 weeks · people requiring intervention for short saphenous vein varices

Endovenous laser ablation probably leads to lower recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (moderate certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Recurrence of reflux at 1 year · people requiring intervention for short saphenous vein varices

Endovenous laser ablation may leads to lower recurrence of reflux at 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Recurrence · people requiring intervention for short saphenous vein varices

Endovenous laser ablation showed no clear difference in clinical evidence of recurrence after 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices
2 findings from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices
2 findings from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recanalisation or persistence of reflux at 6 weeks · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (low certainty).

1 finding from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recurrence of reflux at 1 year · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recurrence of reflux at 1 year compared with conventional surgery (low certainty).

1 finding from 1 review