Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

262 questions · 304 findings · 17 reviews · Dental caries

No studies found 40 · 13.2%GRADE not reported 169 · 55.6%Very low 46 · 15.1%Low 25 · 8.2%Moderate 24 · 7.9%High 0 · 0%

Community and caregiver oral health education plus media campaign vs Pre-intervention baseline (and sites that discontinued the prevention program)

Reduction in prevalence of baby bottle tooth decay (BBTD) · Alaska Native and American Indian Head Start children

Community and caregiver oral health education was associated with a significant ~25% overall reduction in baby bottle tooth decay among Head Start children (certainty not graded).

1 finding from 1 review

Ongoing BBTD Prevention Program vs BBTD Prevention Program discontinued in 1989

Baby bottle tooth decay prevalence · Alaska Native and American Indian Head Start children

Sites discontinuing the prevention program had a non-significant 15% reduction in tooth decay rate, without a GRADE rating.

2 findings from 1 review

DHAT-delivered dental care vs Dentist-delivered dental care

Stainless steel crown preparation and placement deficiency · Alaska dental health aide therapists

No stainless steel crown preparation deficiencies were reported; placement deficiency was 3% for DHATs versus 9% for dentists, without a GRADE rating.

1 finding from 1 review

Primary dental health aide (PDHA) service-delivery models (PDHA program; PDHA + intensive staffing; PDHA + robust prevention) vs Baseline pre-intervention service-delivery scenario

Projected dental care utilisation · Alaska Native children (below age 18)

A simulation projected that the PDHA program would raise dental care utilisation from 75% to 90% (certainty not graded).

1 finding from 1 review

DHAT-delivered dental care vs Dentist-delivered dental care

Quality of dental record keeping by DHATs · Alaska Native dental patients (children aged 6-17 and adults) and their caregivers

Dental record keeping by DHATs was high quality and met Indian Health Service guidelines (certainty not graded).

1 finding from 1 review

Primary school-based behavioural intervention (both oral hygiene and dietary components) vs No treatment (or delayed treatment)

Frequency of cariogenic food and drink consumption · Children aged 4 to 12 years attending primary school
1 finding from 1 review

Community and caregiver oral health education plus media campaign vs Pre-intervention BBTD rate

Baby bottle tooth decay prevalence · Alaska Native Head Start children

The Alaska Native site had a 20% increase in BBTD prevalence, without a GRADE rating.

1 finding from 1 review

Primary school-based behavioural intervention (both oral hygiene and dietary components) vs No treatment (or delayed treatment)

Frequency of toothbrushing · Children aged 4 to 12 years attending primary school
1 finding from 1 review

PDHA program vs Baseline pre-intervention service-delivery scenario

School-based oral health promotion services · Alaska children

The PDHA program was projected to raise school-based oral health promotion service receipt from 53% to more than 90%, without a GRADE rating.

1 finding from 1 review

Primary dental health aide (PDHA) service-delivery models (PDHA program; PDHA + intensive staffing; PDHA + robust prevention) vs Baseline pre-intervention service-delivery scenario

Projected mean DMFT (children below 5 years) · Alaska Native children (below age 18)

A simulation projected mean DMFT in children under 5 would fall from 7.4 to 4.9 under the PDHA model (certainty not graded).

1 finding from 1 review

Mixed beam (neutron and photon) radiotherapy vs Conventional photon radiotherapy

Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…

Mixed beam (neutron and photon) radiotherapy showed no clear difference in locoregional control compared with conventional photon radiotherapy; GRADE not reported.

1 finding from 1 review

Altered fractionation radiotherapy (hyperfractionated and/or accelerated) vs Conventional (standard) fractionation radiotherapy

Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…

Hyperfractionated/accelerated radiotherapy led to lower locoregional control compared with conventional (standard) fractionation radiotherapy; GRADE not reported.

2 findings from 1 review