Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

426 questions · 433 findings · 18 reviews · Implants and prosthodontics

No studies found 45 · 10.4%GRADE not reported 341 · 78.8%Very low 36 · 8.3%Low 6 · 1.4%Moderate 5 · 1.2%High 0 · 0%

Subepithelial connective tissue graft (palate) at implant placement vs No augmentation

Marginal bone level change · Partially edentulous patients receiving posterior mandibular implants

Subepithelial connective tissue graft (palate) at implant placement showed no clear difference in peri-implant marginal bone level change compared with no augmentation; GRADE not reported.

1 finding from 1 review

Ceramic implant abutment vs Metal implant abutments (titanium)

Overall success rate · Patients receiving implant-supported single crowns / short-span FDPs
1 finding from 1 review
  • Andersson 2003: 94% (16/17) ceramic vs 100% (12/12) titanium; Andersson 2001: 93% (28/30) ceramic vs 100% (35/35) titanium; no statistical analysis provided; no measurable / non-significant differences in alveolar bone…
    2 studies · 107 participants
    GRADE not reported

Alternative alloy FDP (e.g., Ceramalloy II / base-metal / palladium-silver) vs High-gold content control alloy FDP (Olympia)

Restoration survival · Patients receiving crowns and FDPs; split-mouth, 10-year

Alternative alloy FDP (e.g., Ceramalloy II / base-metal /… led to higher restoration survival (Ceramalloy II versus Olympia) compared with high-gold content control alloy FDP (Olympia); GRADE not reported.

1 finding from 1 review

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Change in gingival recession (REC) · People with at least one dental implant affected by perimplantitis

Er:YAG laser debridement showed no clear difference in change in gingival recession (REC) compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

1 finding from 1 review

Denzir all-ceramic FDP vs In-Ceram Zirconia all-ceramic FDP

Reconstruction failure / chip fractures (12 months) · Patients with all-ceramic implant FDP reconstructions; parallel group, 12-month
1 finding from 1 review

Subepithelial connective tissue graft (palate) at implant placement vs No augmentation

Aesthetic preference evaluated by the patient (split-mouth design studies) · Partially edentulous patients receiving posterior mandibular implants

Subepithelial connective tissue graft (palate) at implant placement led to lower patient preference (aesthetics evaluated by patients) compared with no augmentation; GRADE not reported.

1 finding from 1 review

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis

Er:YAG laser debridement showed no clear difference in change in probing attachment level (PAL) compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

1 finding from 1 review

RDP with I-bar clasps / mesial rests vs RDP with circumferential clasps / distal rests

Change in abutment tooth mobility at 60 months · Partially edentulous patients treated with a removable dental prosthesis (RDP)

RDP with I-bar clasps / mesial rests showed no clear difference in change in abutment tooth mobility at 60 months compared with RDP with circumferential clasps / distal rests; GRADE not reported.

1 finding from 1 review

Nanocrystalline hydroxyapatite (Ostim) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis

Nanocrystalline hydroxyapatite (Ostim) led to lower change in probing pocket depth (PPD) compared with bovine-derived xenograft (Bio-Oss) plus resorbable barrier; GRADE not reported.

1 finding from 1 review

Laser-welded titanium framework vs Cast gold framework

Framework survival (5 years) · Patients with implant-supported FDPs; split-mouth, 5-year
1 finding from 1 review
  • 95% (20/21) titanium and 100% cast gold frameworks surviving 5 years; could not calculate an estimate of relative risk from the data as presented; non-significant differences in maintenance visits and alveolar bone loss
    1 study · 21 participants
    GRADE not reported

Metronidazole gel 25% (local antibiotic) vs Ultrasonic debridement

Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis

Metronidazole gel 25% (local antibiotic) showed no clear difference in change in probing pocket depth compared with ultrasonic debridement; GRADE not reported.

1 finding from 1 review

Glass ionomer (GIC) permanent cement vs Zinc phosphate cement

Post-operative hypersensitivity, tooth vitality, prosthesis retention and secondary caries · Patients receiving cemented FDPs; split-mouth
1 finding from 1 review

Tooth/implant FDP with rigid connectors vs Tooth/implant FDP with non-rigid connectors

Prosthesis survival and crestal bone loss (5 years) · Patients with tooth/implant-supported FDPs; split-mouth
1 finding from 1 review

Fixed dental prosthesis (cantilever FDP) vs Removable dental prosthesis (RDP)

5-year prosthesis survival · Patients with a shortened dental arch (missing posterior teeth)

Fixed dental prosthesis (cantilever FDP) showed no clear difference in prosthesis survival compared with removable dental prosthesis (RDP); GRADE not reported.

1 finding from 1 review

Erbium:YAG laser vs Air-abrasive device (Perio-Flow)

Recurrence of peri-implantitis · People with at least one dental implant affected by perimplantitis

Er:YAG laser led to lower recurrence of peri-implantitis compared with air-abrasive device (Perio-Flow); GRADE not reported.

1 finding from 1 review