Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

647 questions · 674 findings · 100 reviews

No studies found 129 · 19.1%GRADE not reported 95 · 14.1%Very low 220 · 32.6%Low 142 · 21.1%Moderate 64 · 9.5%High 24 · 3.6%

Supported discharge and multidisciplinary home rehabilitation vs (Optimised) usual care

Mortality (at 4 months) · Older people undergoing hip fracture aftercare

It is very uncertain whether supported discharge and multidisciplinary home rehabilitation changes mortality (at 4 months) compared with usual care: mainly (very low certainty).

1 finding from 1 review

Supported discharge and multidisciplinary home rehabilitation vs (Optimised) usual care

Death by the end of scheduled · Older people undergoing hip fracture aftercare

It is very uncertain whether supported discharge and multidisciplinary home rehabilitation changes mortality (end of scheduled compared with usual care: mainly (very low certainty).

1 finding from 1 review

Supported discharge and multidisciplinary home rehabilitation vs (Optimised) usual care

Independent in personal activities of daily living · Older people undergoing hip fracture aftercare

It is very uncertain whether supported discharge and multidisciplinary home rehabilitation changes independent in personal activities of daily living compared with usual care: mainly (very low certainty).

1 finding from 1 review

Supported discharge and multidisciplinary home rehabilitation vs (Optimised) usual care

Unable to walk · Older people undergoing hip fracture aftercare

It is very uncertain whether supported discharge and multidisciplinary home rehabilitation changes unable to walk compared with usual care: mainly (very low certainty).

1 finding from 1 review

Individualised homeopathic medicine (two doses over 24 hours) vs placebo

Ulcer healing · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Individualised homeopathic medicine (two doses over 24 hours) led to higher complete ulcer healing by end of study (day 6) compared with placebo; GRADE not reported.

1 finding from 1 review

Individualised homeopathic medicine (two doses over 24 hours) vs placebo

Mean pain score and mean ulcer size · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review

Individualised homeopathic medicine (two doses over 24 hours) vs placebo

Pain free by end of study (day 6) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Individualised homeopathic medicine (two doses over 24 hours) led to higher pain free by end of study (day 6) compared with placebo; GRADE not reported.

1 finding from 1 review

12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel, professionally applied every 3 months plus home use vs Placebo gel

Number of participants with new demineralised lesions (DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

It is very uncertain whether 12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel,… changes number of participants with new demineralised lesions (DLs) compared with 0 ppm F placebo gel (very low certainty).

1 finding from 1 review

Breastfeeding promotion and support (e.g. individually tailored home-based peer counselling on the importance of breastfeeding, with advice and support for healthy breastfeeding) vs usual care

Caries presence in primary teeth · For interventions, pregnant and lactating women; for outcomes, children up to 6 years of age

Breastfeeding promotion and support (e.g. individually tailored… showed no clear difference in caries presence in primary teeth compared with standard care (low certainty).

1 finding from 1 review

Breastfeeding promotion and support (e.g. individually tailored home-based peer counselling on the importance of breastfeeding, with advice and support for healthy breastfeeding) vs usual care

Dental caries · For interventions, pregnant and lactating women; for outcomes, children up to 6 years of age

The review found no eligible studies for this question.

2 findings from 1 review

Case management for integrated care vs usual care of older people living with frailty

Change in place of residence to a nursing or residential home · people aged 65 years and older living with frailty

Case management for integrated care showed no clear difference in change in place of residence to a nursing or residential home compared with usual care of older people living with frailty (low certainty).

1 finding from 1 review

Dextrose gel vs control

Correction of hypoglycaemia for each hypoglycaemic event before discharge home (investigator defined) · newborn infants with hypoglycaemia

Oral dextrose gel showed no clear difference in correction of hypoglycaemia for each hypoglycaemic event before… compared with control (moderate certainty).

1 finding from 1 review

Dextrose gel vs control

Receipt of intravenous treatment for hypoglycaemia (yes/no) · newborn infants with hypoglycaemia

It is very uncertain whether oral dextrose gel changes receipt of intravenous treatment for hypoglycaemia before discharge… compared with control (very low certainty).

1 finding from 1 review

Complex information, support and training interventions vs information only

Institutional care ‐ nursing home placement · Informal caregivers of people with dementia

It is very uncertain whether complex information, support and training interventions changes institutional care ‐ nursing home placement compared with information provision only (very low certainty).

1 finding from 1 review

Complex information, support and training interventions vs inactive control (usual care care, attention control, waitlist)

Institutional care ‐ nursing home placement · Informal caregivers of people with dementia

It is very uncertain whether complex information, support and training interventions changes institutional care ‐ nursing home placement compared with usual treatment, waiting list or attention control informations (very low certainty).

1 finding from 1 review