Topiramate vs placebo
Topiramate leads to higher treatment withdrawal compared with placebo (high certainty).
- RR 2.37 [1.66, 3.37]12 studies · 1650 participantsHigh
Topiramate leads to higher treatment withdrawal compared with placebo (high certainty).
Tiagabine probably leads to higher treatment withdrawal compared with placebo control (moderate certainty).
Collaborative case management showed no clear difference in use of primary drug during 9 month compared with treatment (low certainty).
It is very uncertain whether linezolid changes treatment failure compared with no linezolid (very low certainty).
It is very uncertain whether linezolid changes treatment interrupted compared with no linezolid (very low certainty).
It is very uncertain whether linezolid changes treatment completed compared with no linezolid (very low certainty).
It is very uncertain whether linezolid changes antituberculous treatment discontinuationj compared with no linezolid (very low certainty).
It is very uncertain whether specific antipsychotic changes acceptability of the treatment: leaving the study early compared with other drugs (very low certainty).
It is very uncertain whether cognitive‐behavioural coping skills training (CBCST) changes number of participants achieving 3 or more weeks of consecutive… compared with twelve‐step facilitation (TSF) programme to reduce alcohol consumption (very low certainty).
Brief motivational interviewing (BMI) showed no clear difference in retention ‐ end of treatment compared with assessment‐only to reduce alcohol consumption (moderate certainty).
Motivational interviewing intensive (MII) may leads to higher retention ‐ end of treatment compared with motivational interviewing (MI) to reduce alcohol consumption (low certainty).
It is very uncertain whether cognitive‐behavioural coping skills training (CBCST) changes retention ‐ end of treatment compared with twelve‐step facilitation (TSF) programme to reduce alcohol consumption (very low certainty).
It is very uncertain whether tricyclics changes number not achieving 14 consecutive dry nights at the end of… compared with another drug (very low certainty).
FLUPHENAZINE showed no clear difference in response to treatment compared with LOW‐POTENCY ANTIPSYCHOTIC DRUGS (moderate certainty).
FLUPHENAZINE showed no clear difference in acceptability of treatment‐leaving the study early due to any reason compared with LOW‐POTENCY ANTIPSYCHOTIC DRUGS (moderate certainty).