What do systematic reviews say?

Lithium vs antipsychotics

The review found no eligible studies for this question.

• Lithium for schizophrenia 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Lithium vs antipsychotics

The review found no eligible studies for this question.

• Lithium for schizophrenia 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Lithium vs antipsychotics

It is very uncertain whether lithium changes acceptability of treatment leaving early due to any reason compared with antipsychotics (very low certainty).

• Lithium for schizophrenia 2015 · Cochrane Headline outcomes only
  RR 1.77 [1.01, 3.11]
  8 studies · 270 participants
  Very low

Intervention not reported

• Screening women for intimate partner violence in healthcare settings 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 663 participants
  Moderate

Perazine vs OTHER ANTIPSYCHOTICS

Perazine showed no clear difference in acceptability of treatment Leaving the studies early due to any reason compared with other antipsychotics (low certainty).

• Perazine for schizophrenia 2014 · Cochrane Headline outcomes only
  RR 0.97 [0.68, 1.38]
  6 studies · 384 participants
  Low

FLUPENTHIXOL vs LOW‐POTENCY ANTIPSYCHOTIC DRUGS

• Flupenthixol versus low‐potency first‐generation antipsychotic drugs for schizophrenia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

QUETIAPINE vs Typical antipsychotics

Quetiapine showed no clear difference in leaving the study early due to any reason compared with typical antipsychotics (moderate certainty).

• Quetiapine versus typical antipsychotic medications for schizophrenia 2013 · Cochrane Headline outcomes only
  RR 0.91 [0.81, 1.01]
  23 studies · 3576 participants
  Moderate

Benzodiazepines vs antipsychotics

It is very uncertain whether BENZODIAZEPINES changes leaving the study early due to any reason (overall acceptability of… compared with ANTIPSYCHOTICS (very low certainty).

• Benzodiazepines for schizophrenia 2012 · Cochrane Headline outcomes only
  RR 0.73 [0.45, 1.18]
  13 studies · 738 participants
  Very low

Levomepromazine vs Typical antipsychotics

Levomepromazine showed no clear difference in leaving the study early ‐ short term ‐ any reason compared with typical antipsychotics (low certainty).

• Levomepromazine for schizophrenia 2010 · Cochrane Headline outcomes only
  RR 1.11 [0.45, 2.74]
  1 study · 41 participants
  Low

Levomepromazine vs Typical antipsychotics

It is very uncertain whether levomepromazine changes leaving the study early ‐ medium term ‐ any reason compared with typical antipsychotics (very low certainty).

• Levomepromazine for schizophrenia 2010 · Cochrane Headline outcomes only
  RR 2 [0.2, 19.62]
  1 study · 28 participants
  Very low

Levomepromazine vs Typical antipsychotics

Levomepromazine showed no clear difference in leaving the study early ‐ long term ‐ any reason compared with typical antipsychotics (moderate certainty).

• Levomepromazine for schizophrenia 2010 · Cochrane Headline outcomes only
  RR 0.4 [0.09, 1.81]
  1 study · 38 participants
  Moderate

Levomepromazine vs atypical antipsychotics

Levomepromazine showed no clear difference in leaving the study early ‐ short term ‐ any reason compared with atypical antipsychotics (low certainty).

• Levomepromazine for schizophrenia 2010 · Cochrane Headline outcomes only
  RR 1 [0.67, 1.49]
  2 studies · 106 participants
  Low

1-stage (non-submerged) implant placement vs 2-stage (submerged) implant placement

1-stage (non-submerged) implant placement showed no clear difference in aesthetics evaluated by dentists (soft tissue recession) compared with 2-stage (submerged) implant placement; GRADE not reported.

• Interventions for replacing missing teeth: 1- versus 2-stage implant placement 2009 · Cochrane All outcomes

  6 to 12 months after loading
  MD -0.20 [-0.67, 0.27]
  1 study · 29 participants
  GRADE not reported

1-stage (non-submerged) implant placement vs 2-stage (submerged) implant placement

The review found no eligible studies for this question.

• Interventions for replacing missing teeth: 1- versus 2-stage implant placement 2009 · Cochrane All outcomes

  6 to 12 months after loading
  Planned outcome (patient preference including aesthetics, only in split-mouth studies); no included trial reported it.
  0 studies
  No studies found

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

Systemic antibiotic prophylaxis (any regimen; topical therapy… may leads to lower dry socket compared with placebo (low certainty).

• Antibiotics to prevent complications following tooth extractions 2021 · Cochrane All outcomes

  1st to 7th day
  RR 0.66 [0.45, 0.97]
  13 studies · 1882 participants
  Low

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

Systemic antibiotic prophylaxis (any regimen; topical therapy… may leads to lower postsurgical infectious complications compared with placebo (low certainty).

• Antibiotics to prevent complications following tooth extractions 2021 · Cochrane All outcomes

  1st to 14th day
  RR 0.34 [0.19, 0.64]
  12 studies · 1728 participants
  Low

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes swelling (7th day) compared with placebo (very low certainty).

• Antibiotics to prevent complications following tooth extractions 2021 · Cochrane All outcomes

  7th day
  RR 0.80 [0.50, 1.27]
  4 studies · 452 participants
  Very low

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes pain (continuous, VAS 0-10 cm, 7th day) compared with placebo (very low certainty).

• Antibiotics to prevent complications following tooth extractions 2021 · Cochrane All outcomes

  6th to 7th day
  MD -0.26 [-0.59, 0.07]
  4 studies · 422 participants
  Very low

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes presence of pain (dichotomous, yes/no on 6th-7th day) compared with placebo (very low certainty).

• Antibiotics to prevent complications following tooth extractions 2021 · Cochrane All outcomes

  6th to 7th day
  RR 0.59 [0.31, 1.12]
  3 studies · 675 participants
  Very low

Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs placebo

It is very uncertain whether systemic antibiotic prophylaxis (any regimen; topical therapy… changes adverse effects compared with placebo (very low certainty).

• Antibiotics to prevent complications following tooth extractions 2021 · Cochrane All outcomes

  1st to 7th day
  RR 1.46 [0.81, 2.64]
  8 studies · 1277 participants
  Very low