Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,429 questions · 3,558 findings · 436 reviews

No studies found 660 · 18.5%GRADE not reported 375 · 10.5%Very low 727 · 20.4%Low 887 · 24.9%Moderate 709 · 19.9%High 200 · 5.6%

Intervention not reported

False negatives (participants incorrectly classified as not having plague) · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Intervention not reported

True negatives (participants correctly classified as not having plague) · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Intervention not reported

False positives (participants incorrectly classified as having plague) · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Intervention not reported

Test result · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Intervention not reported

True positives (participants correctly classified as having pneumonic plague) · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Intervention not reported

False negatives (participants incorrectly classified as not having pneumonic plague) · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Intervention not reported

True negatives (participants correctly classified as not having pneumonic plague) · s where plague has been known to occur and populations where an outbreak is in progress Patient or population: adults and children with…
1 finding from 1 review

Resin-based fissure sealant (visible-light-polymerized) vs Fluoride varnish

Incidence of dentinal carious lesion on treated occlusal surfaces of molars or premolars (yes/no) · Children and adolescents (general population, aged under 20 years)

It is very uncertain whether resin-based fissure sealant (visible-light-polymerized) changes incidence of dentinal carious lesion on treated occlusal surfaces of… compared with fluoride varnish (very low certainty).

2 findings from 1 review

Resin-modified glass ionomer fissure sealant plus oral health education vs Fluoride varnish plus oral health education

Change in DMF increment on occlusal surfaces of first permanent molars · Children and adolescents (general population, aged under 20 years)

Resin-modified glass ionomer fissure sealant plus oral health… showed no clear difference in change in DMF increment on occlusal surfaces of first permanent molars compared with fluoride varnish plus oral health education; GRADE not reported.

2 findings from 1 review

Resin-based fissure sealant vs Fluoride varnish

Change in DMFT (decayed, missing and filled permanent teeth) increment · Children and adolescents (general population, aged under 20 years)

Resin-based fissure sealant led to lower change in DMFT (decayed, missing and filled permanent teeth) increment compared with fluoride varnish; GRADE not reported.

1 finding from 1 review

Resin-based fissure sealant vs Fluoride varnish

Number of visits to the dentist for repair of sealant or fluoride varnish application · Children and adolescents (general population, aged under 20 years)

Resin-based fissure sealant led to higher number of visits to the dentist for repair of sealant or fluoride… compared with fluoride varnish; GRADE not reported.

1 finding from 1 review

Glass ionomer or resin-modified glass ionomer fissure sealant vs Fluoride varnish

Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review

Resin-based fissure sealant plus fluoride varnish vs Fluoride varnish

Dentine caries in permanent molars (24 months) · Children and adolescents (general population, aged under 20 years)

It is very uncertain whether resin-based fissure sealant plus fluoride varnish changes dentine caries in permanent molars (yes/no) compared with fluoride varnish alone (very low certainty).

1 finding from 1 review