Headache · women with high‐grade VIN
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment discontinuation · women with high‐grade VIN
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Complete response · patients with high‐risk neuroblastoma
Rapid COJEC showed no clear difference in complete response compared with standard induction therapies (low certainty).
1 finding from 1 review
Early toxicities (during preoperative chemotherapy): febrile neutropenia (2 or more episodes), proven fungal infections, septicemia (1 or more episodes), gastrointestinal toxicity (grade 3 or 4), renal toxicity (glomerular filtration rate < 80 ml/... · patients with high‐risk neuroblastoma
1 finding from 1 review
Treatment‐related mortality · patients with high‐risk neuroblastoma
Rapid COJEC showed no clear difference in treatment‐related mortality compared with standard induction therapies (low certainty).
1 finding from 1 review
Overall survival · patients with high‐risk neuroblastoma
Rapid COJEC showed no clear difference in overall survival compared with standard induction therapies (low certainty).
1 finding from 1 review
Progression‐free survival ‐ not reported · patients with high‐risk neuroblastoma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Event‐free survival · patients with high‐risk neuroblastoma
Rapid COJEC showed no clear difference in event‐free survival compared with standard induction therapies (low certainty).
1 finding from 1 review
Late non‐hematological toxicities: any complication, renal toxicity (Glomerular Filtration Rate < 80 ml/min per body surface area of 1.73 m2), ototoxicity (Brock grade 1 to 4), endocrine complications (see table of included studies for included di... · patients with high‐risk neuroblastoma
1 finding from 1 review
Recurrent and persistent bleeding overall rates with or without second‐look endoscopy Rebleeding (persistent or recurrent bleeding) · patients with high‐risk bleeding ulcers
Epinephrine probably leads to lower recurrent and persistent bleeding overall rates with or without… compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
Surgery rate Number requiring emergency surgery · patients with high‐risk bleeding ulcers
Epinephrine probably leads to lower surgery rate Number requiring emergency surgery compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
Mortality rate Number of deaths (30‐day mortality or in‐hospital mortality) · patients with high‐risk bleeding ulcers
Epinephrine probably leads to lower mortality rate Number of deaths (30‐day mortality or in‐hospital… compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
Adverse effects of endoscopy therapy Adverse effects · patients with high‐risk bleeding ulcers
Epinephrine probably leads to higher adverse effects of endoscopy therapy Adverse effects compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
Intervention not reported
Recurrence rate at 1 year · women with high‐grade VIN
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · high‐risk surgical patients with acute calculous cholecystitis.
It is very uncertain whether intervention changes mortality compared with control (very low certainty).
1 finding from 1 review
Serious adverse events · high‐risk surgical patients with acute calculous cholecystitis.
It is very uncertain whether intervention changes serious adverse events compared with control (very low certainty).
1 finding from 1 review
Intervention not reported
Length of hospital stay Days · parents of high‐risk newborn infants
1 finding from 1 review
Deep vein thrombosis · patients with prevention of deep vein thrombosis1
It is very uncertain whether knee length changes deep vein thrombosis (Fixed‐effect analysis) Venous duplex scan,… compared with thigh length graduated compression stockings (very low certainty).
3 findings from 1 review
OR 1.55 [0.78, 3.07]
3 studies · 496 participants
Very low
OR 1.32 [0.43, 4.06]
3 studies · 496 participants
Very low
no estimate extracted
3 studies · 496 participants
Very low
HIV infection · High‐risk HIV‐uninfected individuals (including serodiscordant couples, men who have sex with men and sex workers)
TDF+ FTC probably leads to lower HIV infection compared with placebo (moderate certainty).
1 finding from 1 review
Serious adverse events · High‐risk HIV‐uninfected individuals (including serodiscordant couples, men who have sex with men and sex workers)
TDF+ FTC showed no clear difference in serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review