Cochrane · systematic review · CD007924
Medical interventions for high‐grade vulval intraepithelial neoplasia
Pepas, L, Kaushik, S, Nordin, A, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Gynaecological, Neuro-oncology and Orphan CancerAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
0
No studies
6
Included studies
NR
No studies 6 · 100%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings for imiquimod versus placebo
Population: women with high‐grade VIN
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain ‐ Any grade Summary of findings for imiquimod vs placebo | no estimate extracted | NR | No studies |
Dose reductions Summary of findings for imiquimod vs placebo | no estimate extracted | NR | No studies |
Summary of findings for imiquimod versus cidofovir
Population: women with high‐grade VIN
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain ‐ Any grade Summary of findings for imiquimod vs cidofovir | no estimate extracted | NR | No studies |
Fatigue ‐ Any grade Summary of findings for imiquimod vs cidofovir | no estimate extracted | NR | No studies |
Headache ‐ Any grade Summary of findings for imiquimod vs cidofovir | no estimate extracted | NR | No studies |
Treatment discontinuation Summary of findings for imiquimod vs cidofovir | no estimate extracted | NR | No studies |