Findings

What do systematic reviews say?

3,372 questions · 3,874 findings · 666 reviews

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No studies found 431 · 11.1%GRADE not reported 783 · 20.2%Very low 995 · 25.7%Low 909 · 23.5%Moderate 596 · 15.4%High 160 · 4.1%

Summary of findings: levodopa vs placebo

Quality of life VAS on life satisfaction (0 to 50 = high) · patients with restless legs syndrome

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 60 participants
Moderate

Intervention not reported

Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with peripheral joint osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1835 participants
Low

Intervention not reported

Function (long term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with knee osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1398 participants
High

Intervention not reported

Function (short term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with peripheral joint osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1767 participants
Low

Intervention not reported

Pain (long term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with peripheral joint osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1399 participants
High

Intervention not reported

Function (long term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with peripheral joint osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1398 participants
High

Intervention not reported

Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with knee osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1773 participants
Low

Intervention not reported

Function (short term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with knee osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1767 participants
Low

Intervention not reported

Pain (long term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with knee osteoarthritis

1 finding from 1 review

Acupuncture for peripheral joint osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1399 participants
High

Augmented subscapularis transposition vs subscapularis transposition alone during total shoulder arthroplasty

Pain The Hospital for Special Surgrery 100‐point scoring system. Scale from: 0 to 30 (higher is better). · Patients with rheumatoid shoulder

1 finding from 1 review

Surgical interventions for the rheumatoid shoulder 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Augmented subscapularis transposition vs subscapularis transposition alone during total shoulder arthroplasty

Function The Hospital for Special Surgery 100‐point scoring system. Scale from: 0 to 20 (higher is better). · Patients with rheumatoid shoulder

1 finding from 1 review

Surgical interventions for the rheumatoid shoulder 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Augmented subscapularis transposition vs subscapularis transposition alone during total shoulder arthroplasty

Range of motion The Hospital for Special Surgery 100‐point scoring system . Scale from: 0 to 25 (higher is better). · Patients with rheumatoid shoulder

1 finding from 1 review

Surgical interventions for the rheumatoid shoulder 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

ZOTEPINE vs CLOZAPINE

Mental state: psychopathology Total endpoint data, BPRS (higher score = worse, scale from: 0‐126) · patients with schizophrenia

1 finding from 1 review

Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

ZOTEPINE vs REMOXIPRIDE

Mental state: psychopathology Total endpoint data, BPRS (higher score = worse, scale from: 0‐126) · patients with schizophrenia

1 finding from 1 review

Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Very low

ZOTEPINE vs RISPERIDONE

Mental state: psychopathology Total endpoint data, BPRS (higher score = worse, scale from: 0‐126) · patients with schizophrenia

2 findings from 1 review

Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low
Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Intervention not reported

Global state: Average change (CGI‐I, high=good) · patients with people with schizophrenia who have neuroleptic‐induced weight or metabolic problems

1 finding from 1 review

Antipsychotic switching for people with schizophrenia who have neuroleptic‐induced weight or metabolic problems 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 203 participants
Moderate

Intervention not reported

Mental state: Average change (PANSS, high decline=good) · patients with people with schizophrenia who have neuroleptic‐induced weight or metabolic problems

1 finding from 1 review

Antipsychotic switching for people with schizophrenia who have neuroleptic‐induced weight or metabolic problems 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 198 participants
Low

Total Shoulder Arthroplasty vs hemiarthroplasty

Disability/Function (ASES) American Shoulder and Elbow Surgeons Shoulder Score. Scale from: 0 to 100 (Higher is better). · patients with Shoulder osteoarthritis

1 finding from 1 review

Surgery for shoulder osteoarthritis 2010 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 88 participants
Moderate

LOW DOSE (greater than or equal to 2‐<4 mg/day) vs ANY DOSE ‐ short term

Leaving the study early: any reason ‐ when compared with high dose ( greater than or equal to 10 mg) · patients with schizophrenia

LOW DOSE (greater than or equal to 2‐<4 mg/day) probably leads to higher leaving the study early: any reason ‐ when compared with high dose (… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review

Risperidone dose for schizophrenia 2009 · Cochrane Headline outcomes only
RR 2.33 [1.4, 3.86]
1 study · 70 participants
Moderate

LOW DOSE (greater than or equal to 2‐<4 mg/day) vs ANY DOSE ‐ short term

Global state: No clinically important improvement ‐ global evaluation ‐ when compared with standard‐higher dose (greater than or equal to 6‐<10 mg/day) · patients with schizophrenia

LOW DOSE (greater than or equal to 2‐<4 mg/day) probably leads to higher global state: No clinically important improvement ‐ global… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review

Risperidone dose for schizophrenia 2009 · Cochrane Headline outcomes only
RR 1.32 [1.06, 1.64]
2 studies · 172 participants
Moderate