Diabetes‐related complications (1) Fatal MI (2) Fatal stroke (3) Progression in retinopathy (4) Amputations (5) ESRD
It is very uncertain whether insulin detemir changes diabetes‐related complications (1) Fatal MI (2) Fatal stroke (3)… compared with NPH insulin (very low certainty).
1 finding from 1 review
RR 1.5 [0.68, 3.32]
1 study · 2 participants
Very low
Hypoglycaemic episodes
It is very uncertain whether insulin detemir changes hypoglycaemic episodes (1) Severe hypoglycaemia (2) Serious… compared with NPH insulin (very low certainty).
1 finding from 1 review
RR 0.45 [0.17, 1.2]
1 study · 5 participants
Very low
Recurrence of symptomatic UTI in children · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children compared with placebo or no treatment (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI: cotrimoxazole (1) versus cefprozil (2) · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 showed no clear difference in recurrence of symptomatic UTI: cotrimoxazole (1) versus cefprozil (2) compared with antibiotic 2 (moderate certainty).
2 findings from 1 review
Microbial resistance to prophylactic drugs: nitrofurantoin (1) versus cotrimoxazole (2) · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 probably leads to lower microbial resistance to prophylactic drugs: nitrofurantoin (1)… compared with antibiotic 2 (moderate certainty).
1 finding from 1 review
Adverse events: cotrimoxazole (1) versus cefprozil (2) · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 showed no clear difference in adverse events: cotrimoxazole (1) versus cefprozil (2) compared with antibiotic 2 (low certainty).
1 finding from 1 review
Adverse events: nitrofurantoin (1) versus trimethoprim (2) · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 may leads to higher adverse events: nitrofurantoin (1) versus trimethoprim (2) compared with antibiotic 2 (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children without VUR · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children without VUR compared with placebo or no treatment (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children with VUR · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in recurrence of symptomatic UTI in children with VUR compared with placebo or no treatment (low certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children, in studies with adequate allocation concealment · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment probably leads to lower recurrence of symptomatic UTI in children, in studies with adequate… compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Repeat positive urine culture · children with previous UTI and most do not have a renal tract abnormality such as VUR
It is very uncertain whether antibiotic treatment changes repeat positive urine culture compared with placebo or no treatment (very low certainty).
1 finding from 1 review
All adverse events · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in all adverse events compared with placebo or no treatment (low certainty).
1 finding from 1 review
Microbial resistance to prophylactic drug · children with previous UTI and most do not have a renal tract abnormality such as VUR
Antibiotic treatment showed no clear difference in microbial resistance to prophylactic drug compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Recurrence of symptomatic UTI in children · children with primarily normal renal tracts who have experienced at least one UTI
Antibiotic 1 showed no clear difference in recurrence of symptomatic UTI: cotrimoxazole (1) versus cefadroxil (2) compared with antibiotic 2 (low certainty).
1 finding from 1 review
Intervention not reported
All VTE · patients undergoing abdominal or pelvic surgery
The intervention probably leads to lower all VTE (moderate certainty).
1 finding from 1 review
Intervention not reported
All DVT (sensitivity analysis unpublished) · patients undergoing abdominal or pelvic surgery
The intervention probably leads to lower all DVT (sensitivity analysis unpublished) (moderate certainty).
1 finding from 1 review
Intervention not reported
All DVT · patients undergoing abdominal or pelvic surgery
The intervention probably leads to lower all DVT (moderate certainty).
1 finding from 1 review
Intervention not reported
Proximal DVT · patients undergoing abdominal or pelvic surgery
The intervention probably leads to lower proximal DVT (moderate certainty).
1 finding from 1 review
Intervention not reported
Symptomatic VTE · patients undergoing abdominal or pelvic surgery
The intervention showed no clear difference in symptomatic VTE (moderate certainty).
1 finding from 1 review
Intervention not reported
Bleeding complications · patients undergoing abdominal or pelvic surgery
The intervention showed no clear difference in bleeding complications (moderate certainty).
1 finding from 1 review